Publisher Summary This chapter investigates mitochondrial respiratory complex activity in
mitochondria isolated from human cells and tissues. Mitochondrial cytopathies are a …

Publisher Summary This chapter discusses the methods of assessment of mitochondrial
oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial …

Following the discovery of inhibition of electron transport complex I by the neurotoxin 1‐
methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine (MPTP), which produces a parkinsonian …

Low‐level laser irradiation has been applied in a variety of laboratory studies and clinical
trials for photobiostimulation over the last three decades. Considerable skepticism exists …

The measurement of individual respiratory chain complexes is an important component of
the investigation of diseases due to mitochondrial dysfunction. We have evaluated assays …

Microphotometric assay media for the measurement of succinate dehydrogenase (SDH) and
cytochrome oxidase activities in sections of human skeletal muscle have been developed …

FXTAS (fragile X-associated tremor/ataxia syndrome) is a late-onset neurodegenerative
disorder that affects individuals who are carriers of premutation expansions (55–200 CGG …

This work investigates the effects of oxidative stress due to exhaustive training on
uncoupling protein 2 (UCP2) and Bcl‐2/Bax in rat skeletal muscles. A total of 18 Sprague …

We studied mitochondrial respiratory chain function in skeletal muscle taken from 27
patients with idiopathic Parkinson's disease (PD; 21 Dopa-treated PD patients and 6 de …

We describe a young man with a progressive neurological disorder including myoclonus,
mental retardation, muscle weakness and a mitochondrial myopathy (myoclonus epilepsy …