Osteoporosis is a serious health problem worldwide that is associated with an increased risk
of fractures and mortality. Vascular calcification is a well-defined independent risk factor for …

Osteoprotegerin (OPG) is a glycoprotein that acts as a decoy receptor for receptor activator
of nuclear factor κB ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing …

In the placebo group of the MORE study, including 2576 postmenopausal women (mean
age, 66.5 years), the authors describe a strong linear association between the severity …

Context: Recent animal studies showed that osteocalcin action is related to not only bone
metabolism but also glucose metabolism and fat mass. We investigated the relationship …

Abstract Context: Sclerostin, a Wnt signaling antagonist on the osteoblasts produced by
osteocytes, is regulated by mechanical strain and is implicated in the pathogenesis of disuse …

Context: Receptor activator of nuclear factor-κB ligand (RANKL), receptor activator of
nuclear factor-κB (RANK), and osteoprotegerin (OPG) play a central role in bone remodeling …

Patients with osteoporosis frequently suffer from vascular calcification, which was shown to
predict both cardiovascular morbidity/mortality and osteoporotic fractures. Various common …

Background Cardiovascular diseases are associated with disturbances in calcium
metabolism, including increased urinary calcium, vitamin D insufficiency, and decreased …

Osteocalcin is the most abundant noncollagenous protein of bone matrix. Once transcribed,
this protein undergoes posttranslational modifications within osteoblastic cells before its …

Objective. To investigate whether aorta calcification (AC)–a surrogate marker of
atherosclerosis–is an independent indicator of low bone mass density (BMD), accelerated …