Recently, biomedicine and tissue regeneration have emerged as great advances that
impacted the spectrum of healthcare. This left the door open for further improvement of their …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Skeletal muscle is an essential tissue that attaches to bones and facilitates body
movements. Insulin-like growth factor-1 (IGF-1) is a hormone found in blood that plays an …

Scaffolds are implants or injects, which are used to deliver cells, drugs, and genes into the
body. Different forms of polymeric scaffolds for cell/drug delivery are available:(1) a typical …

The present paper intends to overview a wide range of natural–origin polymers with special
focus on proteins and polysaccharides (the systems more inspired on the extracellular …

Neural tissue engineering (NTE) is a rapidly progressing field that promises to address
several serious neurological conditions that are currently difficult to treat. Selecting the right …

Injuries to the peripheral nervous system (PNS) cause neuropathies that lead to weakness
and paralysis, poor or absent sensation, unpleasant and painful neuropathies, and impaired …

Surgical repair of severe peripheral nerve injuries represents not only a pressing medical
need, but also a great clinical challenge. Autologous nerve grafting remains a golden …

Tissue engineering combines cell and molecular biology with materials and mechanical
engineering to replace damaged or diseased organs and tissues. Fibrin is a critical blood …

Peripheral nerve injuries (PNIs) are the most common injury types to affect the nervous
system. Restoration of nerve function after PNI is a challenging medical issue. Extended …