Metabolic inflammation and insulin resistance in obesity

H Wu, CM Ballantyne - Circulation research, 2020 - Am Heart Assoc
Obesity is becoming an epidemic in the United States and worldwide and increases risk for
many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular …

[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes

F Zatterale, M Longo, J Naderi, GA Raciti… - Frontiers in …, 2020 - frontiersin.org
Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

Adipose tissue inflammation and metabolic dysfunction in obesity

T Kawai, MV Autieri, R Scalia - American Journal of …, 2021 - journals.physiology.org
Several lines of preclinical and clinical research have confirmed that chronic low-grade
inflammation of adipose tissue is mechanistically linked to metabolic disease and organ …

[HTML][HTML] Obesity and obesity-induced inflammatory disease contribute to atherosclerosis: a review of the pathophysiology and treatment of obesity

RJ Henning - American journal of cardiovascular disease, 2021 - ncbi.nlm.nih.gov
Two billion people worldwide older than 18 years of age, or approximately 30% of the world
population, are overweight or obese. In addition, more than 43 million children under the …

The effect of obesity on lung function

AE Dixon, U Peters - Expert review of respiratory medicine, 2018 - Taylor & Francis
Introduction: There is a major epidemic of obesity, and many obese patients suffer with
respiratory symptoms and disease. The overall impact of obesity on lung function is …

Adipokine dysregulation and adipose tissue inflammation in human obesity

X Unamuno, J Gómez‐Ambrosi… - European journal of …, 2018 - Wiley Online Library
Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …

The obese adipose tissue microenvironment in cancer development and progression

DF Quail, AJ Dannenberg - Nature Reviews Endocrinology, 2019 - nature.com
Obesity is associated with both increased cancer incidence and progression in multiple
tumour types, and is estimated to contribute to up to 20% of cancer-related deaths. These …

[HTML][HTML] Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus

MS Burhans, DK Hagman, JN Kuzma… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Mast cells as sources of cytokines, chemokines, and growth factors

K Mukai, M Tsai, H Saito, SJ Galli - Immunological reviews, 2018 - Wiley Online Library
Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …