[HTML][HTML] Platelet-rich products and their application to osteoarthritis

LC Garbin, CS Olver - Journal of equine veterinary science, 2020 - Elsevier
Autologous platelet-rich plasma (PRP) is a biological preparation made from the patient's
own plasma that contains a platelet concentration above the whole blood baseline. Owing to …

A comparative review of autologous conditioned serum and autologous protein solution for treatment of osteoarthritis in horses

L Camargo Garbin, MJ Morris - Frontiers in Veterinary Science, 2021 - frontiersin.org
Many alternative treatments aimed at modulating osteoarthritis (OA) progression have been
developed in the past decades, including the use of cytokine inhibitors. IL-1β is considered …

Extracellular vesicles from equine mesenchymal stem cells decrease inflammation markers in chondrocytes in vitro

M Arévalo‐Turrubiarte, M Baratta, G Ponti… - Equine veterinary …, 2022 - Wiley Online Library
Summary Background Mesenchymal stem cells (MSCs) have been used therapeutically in
equine medicine. MSCs release extracellular vesicles (EVs), which affect cell processes by …

Equine autologous conditioned serum and autologous protein solution

KF Ortved - Veterinary Clinics: Equine Practice, 2023 - vetequine.theclinics.com
Musculoskeletal injuries involving joints, tendons, and ligaments occur commonly in the
horse, especially in those performing in athletic pursuits. Such injuries present challenges …

Regenerative Medicine Applied to Musculoskeletal Diseases in Equines: A Systematic Review

A Pérez Fraile, E González-Cubero… - Veterinary …, 2023 - mdpi.com
Simple Summary Musculoskeletal injuries have significant importance within the field of
equine health, mainly due to their economic and sporting implications in today's world. The …

Effects of autologous conditioned serum, autologous protein solution, and triamcinolone on inflammatory and catabolic gene expression in equine cartilage and …

A Velloso Alvarez, LH Boone, SR Pondugula… - Frontiers in veterinary …, 2020 - frontiersin.org
Autologous conditioned serum (ACS) and autologous protein solution (APS) are newer
therapeutic options for osteoarthritis (OA). Co-culture of cartilage and synovium stimulated …

A one-health perspective: use of hemoderivative regenerative therapies in canine and equine patients

AJ Kaneps - Journal of the American Veterinary Medical …, 2023 - Am Vet Med Assoc
Regenerative medicine therapies have become significant tools for treatment of joint, soft
tissue, and a variety of other conditions in animals and humans. Regenerative medicine …

A survey of clinical usage of non-steroidal intra-articular therapeutics by equine practitioners

A Velloso Alvarez, LH Boone, AP Braim… - Frontiers in Veterinary …, 2020 - frontiersin.org
There are several non-steroidal intra-articular therapeutics (NSIATs) available for use by
equine practitioners for the treatment of performance-limiting joint-related pathology …

Evaluation of autologous protein solution injection for treatment of superficial digital flexor tendonitis in an equine model

AM Gaesser, C Underwood, RL Linardi… - Frontiers in Veterinary …, 2021 - frontiersin.org
Autologous protein solution (APS) has been used anecdotally for intralesional treatment of
tendon and ligament injuries, however, its use in these injuries has never been studied in …

Distinct differences in immunological properties of equine orthobiologics revealed by functional and transcriptomic analysis using an activated macrophage readout …

LM Pezzanite, L Chow, GM Griffenhagen… - Frontiers in Veterinary …, 2023 - frontiersin.org
Introduction Multiple biological therapies for orthopedic injuries are marketed to
veterinarians, despite a lack of rigorous comparative biological activity data to guide …