Adipose stem cells (ASCs) are a crucial element in bone tissue engineering (BTE). They are
easy to harvest and isolate, and they are available in significative quantities, thus offering a …

MicroRNA (miRNA) directs post-transcriptional regulation of a network of genes by targeting
mRNA. Although relatively recent in development, many miRNAs direct differentiation of …

Adipose-derived mesenchymal stem cells (ADSCs) are promising candidate for
regenerative medicine to repair non-healing bone defects due to their high and easy …

The alteration of age‐related molecules in the bone marrow microenvironment is one of the
driving forces in osteoporosis. These molecules inhibit bone formation and promote bone …

Human mesenchymal stem cell (hMSC)-derived exosomes have shown regenerative
effects, but their role in osteogenesis and the underlying mechanism are yet to be …

Recent innovations in bone tissue engineering have introduced biomaterials that generate
oxygen to substitute vasculature. This strategy provides the immediate oxygen required for …

Damage to cells and tissues is one of the driving forces of aging and age‐related diseases.
Various repair systems are in place to counteract this functional decline. In particular, the …

Tissue engineering strategies to construct vascularized bone grafts potentially revolutionize
the treatment of massive bone loss. The surface topography of the grafts plays critical roles …

Limited self-regenerating capacity of human skeleton makes the reconstruction of critical
size bone defect a significant challenge for clinical practice. Aimed for regenerating bone …

Repair of large calvarial bony defect remains a challenge for orthopedic surgeons. Since
microRNAs (miRNAs) modulate the osteogenesis of osteoprogenitor cells, we aimed to …