Computational Approaches to Predict Protein–Protein Interactions in Crowded Cellular Environments

G Grassmann, M Miotto, F Desantis… - Chemical …, 2024 - ACS Publications
Investigating protein–protein interactions is crucial for understanding cellular biological
processes because proteins often function within molecular complexes rather than in …

[HTML][HTML] Antibody drugs targeting SARS-CoV-2: Time for a rethink?

L Liang, B Wang, Q Zhang, S Zhang, S Zhang - Biomedicine & …, 2024 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) heavily burdens human health. Multiple …

Zepyros: A webserver to evaluate the shape complementarity of protein-protein interfaces

M Miotto, L Di Rienzo, L Bo, G Ruocco… - arXiv preprint arXiv …, 2024 - arxiv.org
Shape complementarity of molecular surfaces at the interfaces is a well-known characteristic
of protein-protein binding regions, and it is critical in influencing the stability of the complex …

Lactoferrins in Their Interactions with Molecular Targets: A Structure-Based Overview

R Piacentini, A Boffi, E Milanetti - Pharmaceuticals, 2024 - mdpi.com
Lactoferrins and lactoferrin-derived peptides display numerous functions linked to innate
immunity in mammalians, spanning from antimicrobial to anti-inflammatory and …

The Development of Epitope-Based Recombinant Protein Vaccines against SARS-CoV-2

K Khalid, HX Lim, JS Hwang, CL Poh - The AAPS Journal, 2024 - Springer
The COVID-19 pandemic continues to cause infections and deaths, which are attributable to
the SARS-CoV-2 Omicron variant of concern (VOC). Moderna's response to the declining …