Mycobacterium tuberculosis cell-wall and antimicrobial peptides: a mission impossible?

YM Jacobo-Delgado, A Rodríguez-Carlos… - Frontiers in …, 2023 - frontiersin.org
Mycobacterium tuberculosis (Mtb) is one of the most important infectious agents worldwide
and causes more than 1.5 million deaths annually. To make matters worse, the drug …

Antimicrobial peptides as potential therapeutic agents: a review

S Datta, A Roy - International Journal of Peptide Research and …, 2021 - Springer
The growth of pathogens across the globe is developing at a very fast rate, thus turning into
a worldwide health problem. Since, current treatment alternatives have failed to a large …

Rational design of stapled antimicrobial peptides

YH You, HY Liu, YZ Zhu, H Zheng - Amino Acids, 2023 - Springer
The global increase in antimicrobial drug resistance has dramatically reduced the
effectiveness of traditional antibiotics. Structurally diverse antibiotics are urgently needed to …

Antimicrobial peptides (AMPs): The quintessential 'offense and defense'molecules are more than antimicrobials

S Patel, N Akhtar - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Antimicrobial peptides (AMPs) are cationic amphiphilic molecules with α-helix or β-sheet
linear motifs and linear or cyclic configurations. For their role in 'defense and offense', they …

Role of antimicrobial peptides in treatment and prevention of mycobacterium tuberculosis: a review

K Mehta, P Sharma, S Mujawar, A Vyas - International Journal of Peptide …, 2022 - Springer
Tuberculosis (TB) is one of the leading cause of death worldwide, and the world is fighting
with this global health emergency from the past 25 year. The current clinical interventions for …

Host antimicrobial peptides: the promise of new treatment strategies against tuberculosis

J Arranz-Trullén, L Lu, D Pulido, S Bhakta… - Frontiers in …, 2017 - frontiersin.org
Tuberculosis (TB) continues to be a devastating infectious disease and remerges as a
global health emergency due to an alarming rise of antimicrobial resistance to its treatment …

Effect of helical kink in antimicrobial peptides on membrane pore formation

A Tuerkova, I Kabelka, T Králová, L Sukeník, Š Pokorná… - Elife, 2020 - elifesciences.org
Every cell is protected by a semipermeable membrane. Peptides with the right properties, for
example Antimicrobial peptides (AMPs), can disrupt this protective barrier by formation of …

[HTML][HTML] Interaction between antimicrobial peptides and mycobacteria

T Gutsmann - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2016 - Elsevier
Mycobacteria can cause different severe health problems, including tuberculosis (TB). The
treatment of TB with conventional antibiotics is successful, however, the number of multi …

Characterization of a Potent New-Generation Antimicrobial Peptide of Bacillus

S Choyam, PM Jain, R Kammara - Frontiers in Microbiology, 2021 - frontiersin.org
An antimicrobial peptide [Bacillus antimicrobial peptide (BAMP)] produced by Bacillus
paralicheniformis was isolated from the Indian traditional fermented food and characterized …

Metal–peptide complexes as promising antibiotics to fight emerging drug resistance: New perspectives in tuberculosis

C Di Natale, I De Benedictis, A De Benedictis… - Antibiotics, 2020 - mdpi.com
In metal-peptide interactions, cations form stable complexes through bonds with
coordinating groups as side chains of amino acids. These compounds, among other things …