Regulatory cells and the effect of cancer immunotherapy

M Iglesias-Escudero, N Arias-González… - Molecular cancer, 2023 - Springer
Several mechanisms and cell types are involved in the regulation of the immune response.
These include mostly regulatory T cells (Tregs), regulatory macrophages (Mregs), myeloid …

Immune modulation by mesenchymal stem cells

W Jiang, J Xu - Cell proliferation, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …

Immunomodulation by mesenchymal stem cells (MSCs): mechanisms of action of living, apoptotic, and dead MSCs

ARR Weiss, MH Dahlke - Frontiers in immunology, 2019 - frontiersin.org
Expectations on mesenchymal stem cell (MSC) treatment are high, especially in the fields of
sepsis, transplant medicine, and autoimmune diseases. Various pre-clinical studies have …

Therapeutic potential of mesenchymal stem cells for cancer therapy

A Hmadcha, A Martin-Montalvo, BR Gauthier… - … in bioengineering and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for
regenerative medicine. A large number of studies have shown the beneficial effects of MSC …

The immunomodulatory functions of mesenchymal stromal/stem cells mediated via paracrine activity

Y Zhou, Y Yamamoto, Z Xiao, T Ochiya - Journal of clinical medicine, 2019 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) exist in almost all tissues, possessing the potential
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …

Interactions between mesenchymal stem cells and the immune system

N Li, J Hua - Cellular and Molecular Life Sciences, 2017 - Springer
In addition to being multi-potent, mesenchymal stem cells (MSCs) possess
immunomodulatory functions that have been investigated as potential treatments in various …

Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies

P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Immunosuppressive properties of mesenchymal stem cells: advances and applications

MP De Miguel, S Fuentes-Julian… - Current molecular …, 2012 - ingentaconnect.com
Mesenchymal stem cells (MSCs) have been isolated from a variety of tissues, such as bone
marrow, skeletal muscle, dental pulp, bone, umbilical cord and adipose tissue. MSCs are …

Mechanisms of mesenchymal stromal cell immunomodulation

K English - Immunology and cell biology, 2013 - Wiley Online Library
Multipotent mesenchymal stromal cells (MSCs) have generated considerable interest in the
fields of regenerative medicine, cell therapy and immune modulation. Over the past 5 years …

Mesenchymal stem cell-macrophage crosstalk and maintenance of inflammatory microenvironment homeostasis

D Lu, Y Xu, Q Liu, Q Zhang - Frontiers in cell and developmental …, 2021 - frontiersin.org
Macrophages are involved in almost every aspect of biological systems and include
development, homeostasis and repair. Mesenchymal stem cells (MSCs) have good clinical …