MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance

MA Iqbal, S Arora, G Prakasam, GA Calin… - Molecular aspects of …, 2019 - Elsevier
Lung cancer is the cardinal cause of cancer-related deaths with restricted recourse of
therapy throughout the world. Clinical success of therapies is not very promising due to-late …

Tumor microenvironment differences between primary tumor and brain metastases

B Cacho-Díaz, DR García-Botello… - Journal of Translational …, 2020 - Springer
The present review aimed to discuss contemporary scientific literature involving differences
between the tumor microenvironment (TME) in melanoma, lung cancer, and breast cancer in …

Circular RNA circSATB2 promotes progression of non-small cell lung cancer cells

N Zhang, A Nan, L Chen, X Li, Y Jia, M Qiu, X Dai… - Molecular cancer, 2020 - Springer
Background Lung cancer has high morbidity and mortality worldwide with non-small cell
lung cancer (NSCLC) accounting for 85% of the cases. Therapies for lung cancer have …

Long noncoding RNA MALAT1 promotes brain metastasis by inducing epithelial-mesenchymal transition in lung cancer

L Shen, L Chen, Y Wang, X Jiang, H Xia… - Journal of neuro …, 2015 - Springer
Brain metastasis often has a poor prognosis in patients with advanced non-small cell lung
cancer (NSCLC). Therefore, it is urgent to identify factors associated with lung cancer brain …

[HTML][HTML] Epidemiology and prognosis of brain metastases

KJ Stelzer - Surgical neurology international, 2013 - ncbi.nlm.nih.gov
A substantial, but uncertain, number of patients with cancer develop brain metastases. Risk
of brain metastasis is recognized to vary with type of primary cancer. Within specific types of …

Lung cancer-associated brain metastasis: Molecular mechanisms and therapeutic options

M Yousefi, T Bahrami, A Salmaninejad, R Nosrati… - Cellular Oncology, 2017 - Springer
Background Lung cancer is the most common cause of cancer-related mortality in humans.
There are several reasons for this high rate of mortality, including metastasis to several …

MicroRNA let-7c inhibits migration and invasion of human non-small cell lung cancer by targeting ITGB3 and MAP4K3

B Zhao, H Han, J Chen, Z Zhang, S Li, F Fang, Q Zheng… - Cancer letters, 2014 - Elsevier
MicroRNAs play an important regulatory role in carcinogenesis and cancer metastasis.
Different members of let-7 family have been reported to be decreased in human lung tumors …

MicroRNA-378 is associated with non-small cell lung cancer brain metastasis by promoting cell migration, invasion and tumor angiogenesis

L Chen, S Xu, H Xu, J Zhang, J Ning, S Wang - Medical Oncology, 2012 - Springer
Lung cancer is the leading cause of cancer deaths in the world. Brain metastasis (BM) can
affect about 25% of non-small cell lung cancer (NSCLC) patients during their lifetime. Efforts …

The Role of Exosome-Derived MicroRNA on Lung Cancer Metastasis Progression

I Martinez-Espinosa, JA Serrato, B Ortiz-Quintero - Biomolecules, 2023 - mdpi.com
The high mortality from lung cancer is mainly attributed to the presence of metastases at the
time of diagnosis. Despite being the leading cause of lung cancer death, the underlying …

Predictive value of circulating miR-328 and miR-134 for acute myocardial infarction

F He, P Lv, X Zhao, X Wang, X Ma, W Meng… - Molecular and cellular …, 2014 - Springer
MicroRNA (miRNAs) is demonstrated to be present in the blood of humans and has been
increasingly suggested as a novel biomarker for various pathological processes in the heart …