Tuberculosis remains a global health problem, with an estimated 10.4 million cases and 1.8
million deaths resulting from the disease in 2015. The most lethal and disabling form of …

Tuberculous meningitis is especially common in young children and people with untreated
HIV infection, and it kills or disables roughly half of everyone affected. Childhood disease …

Tuberculous meningitis causes substantial mortality and morbidity in children and adults.
More research is urgently needed to better understand the pathogenesis of disease and to …

The aim of these guidelines is to describe a practical but evidence-based approach to the
diagnosis and treatment of central nervous system tuberculosis in children and adults. We …

Rapid diagnosis and treatment of acute community-acquired bacterial meningitis reduces
mortality and neurological sequelae, but can be delayed by atypical presentation …

Background The diagnosis of tuberculous meningitis is difficult. Discrimination of cases from
those of bacterial meningitis by clinical features alone is often impossible, and current …

Tuberculous meningitis (TM) is difficult to diagnose and treat; clinical features are non-
specific, conventional bacteriology is widely regarded as insensitive, and assessment of …

Uncertainty and doubt dominate all aspects of tuberculous meningitis (TBM). The variable
natural history and accompanying clinical features of TBM hinders the diagnosis. Ziehl …

Central nervous system (CNS) involvement, one of the most devastating clinical
manifestations of tuberculosis (TB) is noted in 5 to 10% of extrapulmonary TB cases, and …

Tuberculous meningitis (TBM) is the most common form of central nervous system
tuberculosis (TB) and has very high morbidity and mortality. TBM is typically a subacute …