Extracellular vesicles (EVs) are biocompatible, nano‐sized secreted vesicles containing
many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their …

The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

To date, no reliable clinically applicable biomarker has been established for Parkinson's
disease. Our results indicate that a long anticipated blood test for Parkinson's disease may …

Extracellular vesicles (EVs) are particles naturally released from cells that are delimited by a
lipid bilayer and are unable to replicate. How the EVs cross the Blood–Brain barrier (BBB) in …

Exosomes and ectosomes, two distinct types of extracellular vesicles generated by all types
of cell, play key roles in intercellular communication. The formation of these vesicles …

There is a long-held consensus that several proteins are unique to small extracellular
vesicles (EVs), such as exosomes. However, recent studies have shown that several of …

Neurodegenerative diseases (NDDs) encompass a range of conditions that involve
progressive deterioration and dysfunction of the nervous system. Some of the common …

Cells from all three domains of life, Archaea, Bacteria and Eukarya, produce extracellular
vesicles (EVs) which are sometimes associated with filamentous structures known as …

Protein S-nitros (yl) ation (SNO) is a posttranslational modification involved in diverse
processes in health and disease and can contribute to synaptic damage in Alzheimer's …

The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has
been demonstrated in a multitude of different in vitro cell systems and in a variety of body …