A subset of autism-associated genes regulate the structural stability of neurons

YC Lin, JA Frei, MBC Kilander, W Shen… - Frontiers in cellular …, 2016 - frontiersin.org
Autism spectrum disorder (ASD) comprises a range of neurological conditions that affect
individuals' ability to communicate and interact with others. People with ASD often exhibit …

An inside job: how endosomal Na+/H+ exchangers link to autism and neurological disease

KC Kondapalli, H Prasad, R Rao - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Autism imposes a major impediment to childhood development and a huge emotional and
financial burden on society. In recent years, there has been rapidly accumulating genetic …

Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24. 32 and a significant overlap with schizophrenia

Molecular autism, 2017 - Springer
Background Over the past decade genome-wide association studies (GWAS) have been
applied to aid in the understanding of the biology of traits. The success of this approach is …

Chromosomal microarray analysis of consecutive individuals with autism spectrum disorders or learning disability presenting for genetic services

JL Roberts, K Hovanes, M Dasouki, AM Manzardo… - Gene, 2014 - Elsevier
Chromosomal microarray analysis is now commonly used in clinical practice to identify copy
number variants (CNVs) in the human genome. We report our experience with the use of the …

A current view on contactin-4,-5, and-6: Implications in neurodevelopmental disorders

A Oguro-Ando, A Zuko, KTE Kleijer… - Molecular and Cellular …, 2017 - Elsevier
Contactins (Cntns) are a six-member subgroup of the immunoglobulin cell adhesion
molecule superfamily (IgCAMs) with pronounced brain expression and function. Recent …

[图书][B] Diet-microbe interactions in the gut: Effects on human health and disease

K Tuohy, D Del Rio - 2014 - books.google.com
Drawing on expert opinions from the fields of nutrition, gut microbiology, mammalian
physiology, and immunology, Diet-Microbe Interactions for Human Health investigates the …

Genetic and neural mechanisms of sleep disorders in children with autism spectrum disorder: a review

Q Ji, SJ Li, JB Zhao, Y Xiong, XH Du, CX Wang… - Frontiers in …, 2023 - frontiersin.org
Background The incidence of sleep disorders in children with autism spectrum disorder
(ASD) is very high. Sleep disorders can exacerbate the development of ASD and impose a …

Association of genetic variants with autism spectrum disorder in Japanese children revealed by targeted sequencing

Y Shiota, T Nishiyama, S Yokoyama… - Frontiers in …, 2024 - frontiersin.org
Introduction: Autism spectrum disorders (ASD) represent a heterogeneous group of
neurodevelopmental disorders with strong genetic predispositions. Although an increasing …

Role of a circadian-relevant gene NR1D1 in brain development: possible involvement in the pathophysiology of autism spectrum disorders

M Goto, M Mizuno, A Matsumoto, Z Yang, EF Jimbo… - Scientific reports, 2017 - nature.com
In our previous study, we screened autism spectrum disorder (ASD) patients with and
without sleep disorders for mutations in the coding regions of circadian-relevant genes, and …

Bio-collections in autism research

J Reilly, L Gallagher, JL Chen, G Leader, S Shen - Molecular autism, 2017 - Springer
Autism spectrum disorder (ASD) is a group of complex neurodevelopmental disorders with
diverse clinical manifestations and symptoms. In the last 10 years, there have been …