During the past decade, an abundance of new evidence highlighted the importance of
inflammation in the development of chronic pathologies such as neurodegeneration, cancer …

The anti-inflammatory effects of phytochemicals, bioactive components from plants having
health benefits, have been heavily investigated in the last several decades. However, the …

Environmental stimuli are known to contribute to psoriasis pathogenesis and that of other
autoimmune diseases, but the mechanisms are largely unknown. Here we show that the aryl …

Background Endothelial cell (EC) injury accelerates the progression of diabetic
macrovascular complications. Hypoxia is an important cause of EC injury. Hypoxia-inducible …

Phytobiotics, also known as phytochemicals or phytogenics, have a wide variety of
biological activities and have recently emerged as alternatives to synthetic antibiotic growth …

Activator protein 1 (AP-1) is a pivotal transcription factor that regulates a wide range of
cellular processes including proliferation, apoptosis, differentiation, survival, cell migration …

Inflammation is an essential immune response characterized by pain, swelling, redness,
heat, and impaired function. A controlled acute inflammatory response is necessary to fight …

Here, we investigate the contribution of long-term hematopoietic stem cells (HSCs LT) to
trained immunity (TI) in the setting of chronic autoimmune disease. Using a mouse model of …

Hepatic metastases are amenable to ablation; however, many patients are not suitable
candidates for such therapy and recurrence is common. The tumor microenvironment is …

Flaxseed (Linum usitatissimum L.) has been associated with numerous health benefits. The
flax plant synthesizes an array of biologically active compounds including peptides or …