Chemotherapy remains a powerful tool to eliminate malignant cells. However, the efficacy of
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …

The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …

Bioresponsive polymers have been widely used in drug delivery because of their
degradability. For example, poly (disulfide) s with repeating disulfide bonds in the main …

Ultrasound (US) is a mechanical wave that can penetrate biological tissues and trigger
complex bioeffects. The mechanisms of US in different diagnosis and treatment are different …

Over the past two decades, polymersomes have been widely investigated for the delivery of
diagnostic and therapeutic agents in cancer therapy. Polymersomes are stable polymeric …

Polymersomes have been extensively investigated for drug delivery as nanocarriers for two
decades due to a series of advantages including high stability under physiological …

Cancer remains a highly lethal disease in the world. Currently, either conventional cancer
therapies or modern immunotherapies are non-tumor-targeted therapeutic approaches that …

Breast cancer due to its high incidence and mortality is the second leading cause of death
among females. On the other hand, nanoparticle-based drug delivery is one of the most …

Napabucasin, undergoing multiple clinical trials, was reported to inhibit the signal
transducer and transcription factor 3 (STAT3). To better elucidate its mechanism of action …

High recurrence and metastasis to vital organs are the major characteristics of triple-
negative breast cancer (TNBC). Low vascular oxygen tension promotes resistance to chemo …