Endothelium-Mimicking Materials: A “Rising Star” for Antithrombosis

D Fan, X Liu, H Chen - ACS Applied Materials & Interfaces, 2024 - ACS Publications
The advancement of antithrombotic materials has significantly mitigated the thrombosis
issue in clinical applications involving various medical implants. Extensive research has …

A biodegradable metal‐polymer composite stent safe and effective on physiological and serum‐containing biomimetic conditions

H Zhang, W Zhang, H Qiu, G Zhang, X Li… - Advanced …, 2022 - Wiley Online Library
The new‐generation coronary stents are expected to be biodegradable, and then the
biocompatibility along with biodegradation becomes more challenging. It is a critical issue to …

[HTML][HTML] Polyelectrolytes and Polyelectrolyte Complexes as Future Antibacterial Agents

R Alsayyed, A Ribeiro, H Cabral-Marques - Bacteria, 2024 - mdpi.com
Antibiotic-resistance (ABR) poses a critical public health challenge within the broader
antimicrobial resistance crisis. This review evaluates the potential of polyelectrolytes (PEs) …

Enhanced blood coagulation and antibacterial activities of carboxymethyl-kappa-carrageenan-containing nanofibers

LYC Madruga, KC Popat, RC Balaban, MJ Kipper - Carbohydrate polymers, 2021 - Elsevier
Ideal wound dressings should be biocompatible, exhibit high antibacterial activity, and
promote blood coagulation. To impart these imperative functions, carboxymethyl-kappa …

Vascular cell behavior on glycocalyx–mimetic surfaces: Simultaneous mimicking of the chemical composition and topographical structure of the vascular endothelial …

X Liang, A Zhang, W Sun, J Lei, X Liu, Z Tang… - Colloids and Surfaces B …, 2022 - Elsevier
The endothelial glycocalyx is a carbohydrate–rich layer overlying the outermost surface of
endothelial cells. It mediates intercellular interactions by specific chemical compositions (eg …

Cell-inspired selective potassium removal towards hyperkalemia therapy by microphase-isolated core-shell microspheres

Z Wang, R Yuan, P Li, Y Huang, W Zhao, C Zhao - Acta Biomaterialia, 2023 - Elsevier
Hyperkalemia is a common metabolic problem in patients with chronic kidney disease.
Although oral medications and hemodialysis are clinically applied for lowering serum …

Characterizing thrombus adhesion strength on common cardiovascular device materials

V Kannojiya, SE Almasy, JL Monclova… - … in Bioengineering and …, 2024 - frontiersin.org
Thrombus formation in blood-contacting medical devices is a major concern in the medical
device industry, limiting the clinical efficacy of these devices. Further, a locally formed clot …

Visualizing molecular deformation in fibrin networks under tensile loading via FLIM–FRET

M Hedayati, YI Chen, JR Houser, Y Wang… - Chemical …, 2023 - pubs.rsc.org
Mapping molecular deformation and forces in protein biomaterials is critical to
understanding mechanochemistry. Here we use intramolecular Förster resonance energy …

Incorporating Anticoagulant and Antiplatelet Dual Functional Groups into Thermosetting Polymer Chain for Enhancing Antithrombogenicity

W Wang, S Liu, S Zhang, J Zhang… - Advanced Healthcare …, 2023 - Wiley Online Library
In clinical practice, high‐effective antithrombosis remains a challenge for blood‐contacting
medical devices. Inspired by the enhanced antithrombogenicity of anticoagulant and …

Modifications to Polysaccharide Polyelectrolyte Multilayers: Improved Mechanical Stability and Hemocompatibility

JR Vlcek, LYC Madruga, MM Reynolds… - ACS Applied Polymer …, 2022 - ACS Publications
Cardiovascular implant surfaces and blood-contacting components of extracorporeal blood
circuits induce blood clot formation (thrombosis) and red blood cell lysis (hemolysis) when in …