Genetics and epigenetics of chronic rhinosinusitis

D Lal, T Brar, SP Ramkumar, J Li, A Kato… - Journal of Allergy and …, 2023 - Elsevier
Discerning the genetics and epigenetics of chronic rhinosinusitis (CRS) may optimize
outcomes through early diagnostics, personalized and novel therapeutics, and early …

[HTML][HTML] European position paper on rhinosinusitis and nasal polyps 2020

WJ Fokkens, VJ Lund, C Hopkins, PW Hellings, R Kern… - 2020 - observatorio.fm.usp.br
Resumo The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the
update of similar evidence based position papers published in 2005 and 2007 and 2012 …

[HTML][HTML] Chronic rhinosinusitis in the era of CFTR modulator therapy

RG Stone, C Short, JC Davies, P McNally - Journal of Cystic Fibrosis, 2024 - Elsevier
Chronic rhinosinusitis is a common manifestation of CF that is associated with impaired
quality of life and can be difficult to treat. CFTR modulator therapy has resulted in significant …

[HTML][HTML] Effect of highly effective modulator treatment on sinonasal symptoms in cystic fibrosis

E DiMango, J Overdevest, C Keating, SF Francis… - Journal of Cystic …, 2021 - Elsevier
Background Elexacaftor-tezacaftor-ivacaftor is a highly effective modulator for cystic fibrosis
(CF) patients homozygous or heterozygous for F508del. Effects of the drug on sinonasal …

Cystic Fibrosis Foundation otolaryngology care multidisciplinary consensus recommendations

AJ Kimple, BA Senior, ET Naureckas… - International forum of …, 2022 - Wiley Online Library
Background Cystic fibrosis (CF) is a multisystem disease that often requires otolaryngology
care. Individuals with CF commonly have chronic rhinosinusitis but also present with hearing …

Chronic rhinosinusitis in cystic fibrosis: a review of therapeutic options

J Krajewska, K Zub, A Słowikowski… - European Archives of Oto …, 2022 - Springer
Purpose Chronic rhinosinusitis (CRS) is observed in almost 100% of patients with cystic
fibrosis (CF). CF-related CRS treatment is extremely challenging because of the underlying …

Chronic rhinosinusitis in cystic fibrosis: diagnosis and medical management

C Safi, Z Zheng, E Dimango, C Keating, DA Gudis - Medical Sciences, 2019 - mdpi.com
Chronic rhinosinusitis (CRS) is nearly ubiquitous in patients with cystic fibrosis (CF). CF
CRS is a challenging entity to define, diagnose, and treat, as patients often have severe …

The management of cystic fibrosis chronic rhinosinusitis: an evidenced‐based review with recommendations

DB Spielman, DM Beswick, AJ Kimple… - International forum of …, 2022 - Wiley Online Library
Background Cystic fibrosis (CF) chronic rhinosinusitis (CRS) has emerged as a distinct
diagnostic entity, unique from other endotypes of CRS in its presentation, pathophysiology …

Upper airway disease in adults with cystic fibrosis in the era of CFTR modulators

S Uyttebroek, L Dupont, M Jorissen… - The …, 2023 - Wiley Online Library
Objectives Chronic rhinosinusitis (CRS) is prevalent in people with cystic fibrosis (PwCF)
and is often refractory to treatments. Uncontrolled CRS might negatively impact the lower …

Diagnosing Cystic Fibrosis in the 21st Century—A Complex and Challenging Task

DT Anton-Păduraru, AN Azoicăi, F Trofin, DE Mîndru… - Diagnostics, 2024 - mdpi.com
Cystic fibrosis (CF) is a chronic and potentially life-threatening condition, wherein timely
diagnosis assumes paramount significance for the prompt initiation of therapeutic …