Arsenic intoxication represents a worldwide health problem and occurs mainly through
drinking water. Arsenic, a metalloid and naturally occurring element, is one of the most …

Arsenic is a key environmental toxicant having significant impacts on human health. Millions
of people in developing countries such as Bangladesh, Mexico, Taiwan, and India are …

Endoplasmic reticulum (ER) is a dynamic organelle that participates in a number of cellular
functions by controlling lipid metabolism, calcium stores, and proteostasis. Under stressful …

Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …

Significance: Essential metals such as copper, iron, manganese, and zinc play a role as
cofactors in the activity of a wide range of processes involved in cellular homeostasis and …

Abstract Development of the mammalian central nervous system is a complex process
whose disruption may have severe and long-lasting consequences upon brain structure and …

Arsenic is a metalloid found in groundwater as a byproduct of soil/rock erosion and industrial
and agricultural processes. This xenobiotic elicits its toxicity through different mechanisms …

Arsenic is a toxic metalloid present ubiquitously on earth. Since the last decade, it has
gained considerable attention due to its severe neurotoxic effects. Arsenic can cross the …

Cells respond to environmental stress by regulating gene expression at the level of both
transcription and translation. The∼ 50 modified ribonucleotides of the human …