The acronym nonalcoholic fatty-liver disease (NAFLD) groups a heterogeneous patient
population. Although in many patients the primary driver is metabolic dysfunction, a complex …

The gut microbiome is a key factor in determining inter-individual variability in response to
diet. Thus far, research in this area has focused on metabolic health outcomes such as …

Importance Childhood obesity is a risk factor associated with type 2 diabetes, cardiovascular
disease, and mental disorders later in life. Investigation of the parallel effects of a defined …

In general, it is well recognized that both acute physical exercises and regular physical
training influence brain plasticity and cognitive functions positively. However, growing …

Key points Performing resistance exercise with heavier loads is often proposed to be
necessary for the recruitment of larger motor units and activation of type II muscle fibres …

Background The reactive strength index (RSI) is meaningfully associated with independent
markers of athletic (eg, linear sprint speed) and neuromuscular performance [eg, stretch …

Exercise confers numerous salutary effects that extend beyond individual organ systems to
provide systemic health benefits. Here, we discuss the role of exercise in cardiovascular …

Understanding the factors that contribute to exercise response variation is the first step in
achieving the goal of developing personalized exercise prescriptions. This review discusses …

Precision medicine defines the attempt to identify the most effective approaches for specific
subsets of patients based on their genetic background, clinical features, and environmental …

Background: Many reports describe statistical approaches for estimating interindividual
differences in trainability and classifying individuals as “responders” or “non-responders.” …