Treatment of posttraumatic stress disorder: a state-of-the-art review

L Burback, S Brult-Phillips, MJ Nijdam… - Current …, 2024 - benthamdirect.com
This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

The hypothalamic-pituitary-adrenal axis in PTSD: Pathophysiology and treatment interventions

BW Dunlop, A Wong - Progress in Neuro-psychopharmacology and …, 2019 - Elsevier
Questions of how altered functioning of the hypothalamic pituitary adrenal (HPA) axis
contribute to the development and maintenance of posttraumatic stress disorder (PTSD) …

A unifying translational framework to advance treatment research for comorbid PTSD and substance use disorders

DA Hien, T López-Castro, S Fitzpatrick… - Neuroscience & …, 2021 - Elsevier
We provide a unifying translational framework that can be used to synthesize extant lines of
human laboratory research in four neurofunctional domains that underlie the co-occurrence …

Curculigoside facilitates fear extinction and prevents depression-like behaviors in a mouse learned helplessness model through increasing hippocampal BDNF

S Yang, Z Song, X Wang, Z Zhang, S Wu… - Acta Pharmacologica …, 2019 - nature.com
Curculigoside (CUR) is the main active component of traditional Chinese medicine
Curculigoorchioides Gaertn (Xianmao in Chinese), which exhibits a variety of …

Pharmacological memory modulation to augment trauma-focused psychotherapy for PTSD: a systematic review of randomised controlled trials

L Meister, AC Dietrich, M Stefanovic, F Bavato… - Translational …, 2023 - nature.com
Trauma-focused psychotherapy (tf-PT) is the first-line treatment for posttraumatic stress
disorder (PTSD). Tf-PT focuses on processing and modulating trauma memories. Not all …

Pharmacotherapy for post traumatic stress disorder (PTSD)

T Williams, NJ Phillips, DJ Stein… - Cochrane Database of …, 2022 - cochranelibrary.com
Pharmacotherapy for post traumatic stress disorder (PTSD) - Williams, T - 2022 | Cochrane
Library Skip to Content Cookies Our site uses cookies to improve your experience. You can …

Effects of RU486 in treatment of traumatic stress-induced glucocorticoid dysregulation and fear-related abnormalities: Early versus late intervention

CC Lin, PY Cheng, M Hsiao, YP Liu - International journal of molecular …, 2022 - mdpi.com
Central glucocorticoid receptor (GR) activity is enhanced following traumatic events, playing
a key role in the stress-related cognitive abnormalities of posttraumatic stress disorder …

Treatment approaches for posttraumatic stress disorder derived from basic research on fear extinction

JL Maples-Keller, L Watkins, N Hellman, NL Phillips… - Biological …, 2024 - Elsevier
This brief review article will describe treatment approaches for posttraumatic stress disorder
(PTSD) based on findings from basic research. The focus of this review will be fear …

When translational neuroscience fails in the clinic: Dexamethasone prior to virtual reality exposure therapy increases drop-out rates

JL Maples-Keller, T Jovanovic, BW Dunlop… - Journal of anxiety …, 2019 - Elsevier
Posttraumatic stress disorder (PTSD) is characterized by exaggerated expression of fear
responses to danger and safety cues. Translational research suggests that dexamethasone …

Comparative efficacy and acceptability of pharmaceutical management for adults with post-traumatic stress disorder: a systematic review and meta-analysis

ZD Huang, YF Zhao, S Li, HY Gu, LL Lin… - Frontiers in …, 2020 - frontiersin.org
The current clinical guidelines on post-traumatic stress disorder (PTSD) recommend
selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake …