Structural changes involving tissue remodelling and fibrosis are major features of many
pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD) and …

The respiratory epithelium provides a physical, functional, and immunologic barrier to
protect the host from the potential harming effects of inhaled environmental particles and to …

Allergic rhinitis (AR), chronic rhinosinusitis (CRS) and asthma often co‐exist. The one airway
model proposes that disease mechanisms occurring in the upper airway may mirror lower …

A characteristic feature of the human airway epithelium is the presence of ciliated cells
bearing motile cilia, specialized cell surface projections containing axonemes composed of …

Asthma is the leading chronic disease among children in most industrialized countries.
However, the evidence base on specific aspects of pediatric asthma, including therapeutic …

Background: The accurate diagnosis of latent tuberculosis infection (LTBI) is an important
component of any tuberculosis control programme and depends largely on tuberculin skin …

Remodeling of the airway wall occurs in adults with asthma, and reticular basement
membrane (RBM) thickening is pathognomonic of the asthma process. To investigate …

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ARTICLECredit can now be obtained, free for a limited time, by reading the following review …

Airway remodelling is a critical feature of chronic bronchial diseases, characterised by
aberrant repair of the epithelium and accumulation of fibroblasts, which contribute to …

Rationale: We hypothesized that the epithelial reticular basement membrane (RBM)
thickening and eosinophilic inflammation characteristic of asthma would be present in …