The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Alternatives to conventional antibiotics in the era of antimicrobial resistance

C Ghosh, P Sarkar, R Issa, J Haldar - Trends in microbiology, 2019 - cell.com
As more antibiotics are rendered ineffective by drug-resistant bacteria, focus must be shifted
towards alternative therapies for treating infections. Although several alternatives already …

Janus nanoparticles targeting extracellular polymeric substance achieve flexible elimination of drug-resistant biofilms

Z Liu, K Guo, L Yan, K Zhang, Y Wang, X Ding… - Nature …, 2023 - nature.com
Safe and efficient antibacterial materials are urgently needed to combat drug-resistant
bacteria and biofilm-associated infections. The rational design of nanoparticles for flexible …

[HTML][HTML] Construction and function of robust and moist bilayer chitosan-based hydrogel wound dressing

J Lu, X Fan, J Hu, J Li, J Rong, W Wang, Y Chen… - Materials & Design, 2023 - Elsevier
The main limit of hydrogel used as an independent wound dressing is its poor water
retention, brittleness, and weak skin adhesion. Focusing on it, the macromolecular cross …

Green fabrication of amphiphilic quaternized β‐chitin derivatives with excellent biocompatibility and antibacterial activities for wound healing

H Xu, Z Fang, W Tian, Y Wang, Q Ye… - Advanced …, 2018 - Wiley Online Library
Bacterial infection has always been a great threat to public health, and new antimicrobials to
combat it are urgently needed. Here, a series of quaternized β‐chitin derivatives is prepared …

Antimicrobial and antifouling strategies for polymeric medical devices

ZK Zander, ML Becker - 2018 - ACS Publications
Hospital-acquired infections arising from implanted polymeric medical devices continue to
pose a significant challenge for medical professionals and patients. Often times, these …

Recent progress in polymer research to tackle infections and antimicrobial resistance

MM Konai, B Bhattacharjee, S Ghosh… - …, 2018 - ACS Publications
Global health is increasingly being threatened by the rapid emergence of drug-resistant
microbes. The ability of these microbes to form biofilms has further exacerbated the scenario …

Antimicrobial polymeric nanoparticles

SJ Lam, EHH Wong, C Boyer, GG Qiao - Progress in polymer science, 2018 - Elsevier
Currently, infections caused by multidrug-resistant bacteria have reached critical levels.
Thus, various approaches are being explored for the development of new and effective …

Biomimetic antimicrobial polymers: Recent advances in molecular design

C Ergene, K Yasuhara, EF Palermo - Polymer Chemistry, 2018 - pubs.rsc.org
The increasing prevalence of antibiotic-resistant bacterial infections, coupled with the
decline in the number of new antibiotic drug approvals, has created a therapeutic gap that …

Ag nanoparticles cluster with pH‐triggered reassembly in targeting antimicrobial applications

X Xie, TC Sun, J Xue, Z Miao, X Yan… - Advanced Functional …, 2020 - Wiley Online Library
Antibacterial efficiency can be effectively improved by applying targeting antibacterial
materials and strategies. Herein, the successful synthesis of uniform pH‐responsive Ag …