Sleep spindles: mechanisms and functions

LMJ Fernandez, A Lüthi - Physiological reviews, 2020 - journals.physiology.org
Sleep spindles are burstlike signals in the electroencephalogram (EEG) of the sleeping
mammalian brain and electrical surface correlates of neuronal oscillations in thalamus. As …

On the cellular and network bases of epileptic seizures

DA McCormick, D Contreras - Annual review of physiology, 2001 - annualreviews.org
▪ Abstract The highly interconnected networks of the mammalian forebrain can generate a
wide variety of synchronized activities, including those underlying epileptic seizures, which …

The thalamic reticular nucleus: structure, function and concept

D Pinault - Brain research reviews, 2004 - Elsevier
On the basis of theoretical, anatomical, psychological and physiological considerations,
Francis Crick (1984) proposed that, during selective attention, the thalamic reticular nucleus …

Electrical synapses in the mammalian brain

BW Connors, MA Long - Annu. Rev. Neurosci., 2004 - annualreviews.org
▪ Abstract Many neurons in the mammalian central nervous system communicate through
electrical synapses, defined here as gap junction–mediated connections. Electrical …

Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts

RD Traub, D Contreras… - Journal of …, 2005 - journals.physiology.org
To better understand population phenomena in thalamocortical neuronal ensembles, we
have constructed a preliminary network model with 3,560 multicompartment neurons …

Dynamics of non-convulsive epileptic phenomena modeled by a bistable neuronal network

P Suffczynski, S Kalitzin, FHL Da Silva - Neuroscience, 2004 - Elsevier
It is currently believed that the mechanisms underlying spindle oscillations are related to
those that generate spike and wave (SW) discharges. The mechanisms of transition …

Thalamic synchrony and dynamic regulation of global forebrain oscillations

JR Huguenard, DA McCormick - Trends in neurosciences, 2007 - cell.com
The circuitry within the thalamus creates an intrinsic oscillatory unit whose function depends
critically on reciprocal synaptic connectivity between excitatory thalamocortical relay …

Thalamic inhibition: diverse sources, diverse scales

MM Halassa, L Acsády - Trends in neurosciences, 2016 - cell.com
The thalamus is the major source of cortical inputs shaping sensation, action, and cognition.
Thalamic circuits are targeted by two major inhibitory systems: the thalamic reticular nucleus …

Electrical synapses in the thalamic reticular nucleus

CE Landisman, MA Long, M Beierlein… - Journal of …, 2002 - Soc Neuroscience
Neurons of the thalamic reticular nucleus (TRN) provide inhibitory input to thalamic relay
cells and generate synchronized activity during sleep and seizures. It is widely assumed that …

Reciprocal inhibitory connections and network synchrony in the mammalian thalamus

MM Huntsman, DM Porcello, GE Homanics… - Science, 1999 - science.org
Neuronal rhythmic activities within thalamocortical circuits range from partially synchronous
oscillations during normal sleep to hypersynchrony associated with absence epilepsy. It has …