Zinc finger proteins (ZNF) are among the most abundant proteins in eukaryotic genomes. It
contains several zinc finger domains that can selectively bind to certain DNA or RNA and …

C6 deamination of adenosine (A) to inosine (I) in double-stranded RNA (dsRNA) is
catalyzed by a family of enzymes known as ADARs (adenosine deaminases acting on RNA) …

The RNA editing enzyme adenosine deaminase acting on RNA 1 (ADAR1) is essential for
correct functioning of innate immune responses. The ADAR1p110 isoform is mainly nuclear …

Genetic information is generally transferred from RNA to protein according to the classic
“Central Dogma”. Here, we made a striking discovery that post-translational modification of a …

Adenosine-to-inosine RNA editing is catalyzed by adenosine deaminase acting on RNA
(ADAR) enzymes that deaminate adenosine to inosine. Although many RNA editing sites …

Alternative splicing increases neuronal transcriptomic complexity throughout animal
phylogeny. To delve into the mechanisms controlling the assembly and evolution of this …

The hydrolytic deamination of adenosine-to-inosine (A-to-I) by RNA editing is a widespread
post-transcriptional modification catalyzed by the a denosine dea minase acting on R NA …

RNA-editing by adenosine deaminases acting on RNA (ADARs) converts adenosines to
inosines in structured RNAs. Inosines are read as guanosines by most cellular machineries …

Abstract Adenosine-to-inosine (A-to-I) RNA editing, constituting nearly 90% of all RNA
editing events in humans, has been reported to contribute to the tumorigenesis in diverse …

Detection of viral double-stranded RNA (dsRNA) is an important component of innate
immunity. However, many endogenous RNAs containing double-stranded regions can be …