New Horizons in Myotonic Dystrophy Type 1: Cellular Senescence as a Therapeutic Target
ABSTRACT Myotonic dystrophy type 1 (DM1) is considered a progeroid disease (ie, causing
premature aging). This hypervariable disease affects multiple systems, such as the …
premature aging). This hypervariable disease affects multiple systems, such as the …
[HTML][HTML] Skeletal muscle disorders as risk factors for type 2 diabetes.
The incidence and prevalence of muscular disorders and of type 2 diabetes (T2D) is
increasing and both represent highly significant healthcare problems, both economically …
increasing and both represent highly significant healthcare problems, both economically …
Studying the Effect of MBNL1 and MBNL2 Loss in Skeletal Muscle Regeneration
RS Yadava, M Mandal, MS Mahadevan - International Journal of …, 2024 - mdpi.com
Loss of function of members of the muscleblind-like (MBNL) family of RNA binding proteins
has been shown to play a key role in the spliceopathy of RNA toxicity in myotonic dystrophy …
has been shown to play a key role in the spliceopathy of RNA toxicity in myotonic dystrophy …
[HTML][HTML] Disturbance of the human gut microbiota in patients with Myotonic Dystrophy type 1
M Mahdavi, K Prévost, P Balthazar, IFP Hus… - Computational and …, 2024 - Elsevier
Abstract Myotonic dystrophy type 1 (DM1) is a rare autosomal dominant genetic disorder.
Although DM1 is primarily characterized by progressive muscular weakness, it exhibits …
Although DM1 is primarily characterized by progressive muscular weakness, it exhibits …
Senescent cells inhibit mouse myoblast differentiation via the SASP-lipid 15d-PGJ2 mediated modification and control of HRas
SS Pundlik, A Barik, A Venkateshvaran, SS Sahoo… - Elife, 2024 - elifesciences.org
Senescent cells are characterized by multiple features such as increased expression of
senescence-associated β-galactosidase activity (SA β-gal) and cell cycle inhibitors such as …
senescence-associated β-galactosidase activity (SA β-gal) and cell cycle inhibitors such as …
Muscle stem cells in Duchenne muscular dystrophy exhibit molecular impairments and altered cell fate trajectories impacting regenerative capacity
JA Granet, R Robertson, RL Filippelli, A Cusmano, S Li… - bioRxiv, 2024 - biorxiv.org
Satellite cells are muscle-resident stem cells that maintain and repair muscle. Increasing
evidence supports the contributing role of satellite cells in Duchenne muscular dystrophy …
evidence supports the contributing role of satellite cells in Duchenne muscular dystrophy …
Restoring myogenesis in myotonic dystrophy
H Wood - Nature reviews. Neurology, 2023 - search.proquest.com
The 2023 Alzheimer's Association International Conference (AAIC) held in Amsterdam,
Netherlands (16–20 July 2023) was attended in person by over 7,000 delegates, with even …
Netherlands (16–20 July 2023) was attended in person by over 7,000 delegates, with even …
Análisis comparativo del transcriptoma DM1 a nivel de poliadenilación alternativa e identificación de eventos de cambio de podio
MA Ger Herrera - 2024 - repositorio.uisek.edu.ec
La distrofia miotónica tipo 1 (DM1) es una enfermedad genética autosómica dominante
causada por la expansión de repeticiones de microsatélites en el gen DMPK, caracterizada …
causada por la expansión de repeticiones de microsatélites en el gen DMPK, caracterizada …
Efecto del tratamiento con vesículas extracelulares de células madre de tejido adiposo de ratones jóvenes sobre parámetros de envejecimiento y longevidad en …
N Romero García - 2024 - roderic.uv.es
Introducción El envejecimiento es un proceso universal y progresivo de deterioro de las
funciones orgánicas del individuo. La alteración en la comunicación intercelular es un sello …
funciones orgánicas del individuo. La alteración en la comunicación intercelular es un sello …