Algorithms for de-novo sequencing of peptides by tandem mass spectrometry: a review

CCA Ng, Y Zhou, ZP Yao - Analytica Chimica Acta, 2023 - Elsevier
Peptide sequencing is of great significance to fundamental and applied research in the
fields such as chemical, biological, medicinal and pharmaceutical sciences. With the rapid …

Comparative analysis of commonly used bioinformatics software based on omics

M Xu, C Xu, M Chen, Z Xiao, Y Wang, Y Xu, D Xu - Gene Reports, 2023 - Elsevier
As a widely used technology at the intersection of multiple disciplines in the field of natural
sciences, bioinformatics has received much attention from scholars for its development and …

Multimodal Mass Spectrometry Identifies a Conserved Protective Epitope in S. pyogenes Streptolysin O

D Tang, C Gueto-Tettay, E Hjortswang… - Analytical …, 2024 - ACS Publications
An important element of antibody-guided vaccine design is the use of neutralizing or
opsonic monoclonal antibodies to define protective epitopes in their native three …

Accounting for digestion enzyme bias in Casanovo

C Melendez, J Sanders, M Yilmaz… - Journal of Proteome …, 2024 - ACS Publications
A key parameter of any bottom-up proteomics mass spectrometry experiment is the identity
of the enzyme that is used to digest proteins in the sample into peptides. The Casanovo de …

Comprehensive evaluation of peptide de novo sequencing tools for monoclonal antibody assembly

D Beslic, G Tscheuschner, BY Renard… - Briefings in …, 2023 - academic.oup.com
Monoclonal antibodies are biotechnologically produced proteins with various applications in
research, therapeutics and diagnostics. Their ability to recognize and bind to specific …

Origins, Technological Advancement, and Applications of Peptidomics

M Schrader - Peptidomics: Methods and Strategies, 2024 - Springer
Peptidomics is the comprehensive characterization of peptides from biological sources
instead of heading for a few single peptides in former peptide research. Mass spectrometry …