Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men

A Granic, K Suetterlin, T Shavlakadze… - Clinical …, 2023 - portlandpress.com
Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …

Sarcopenic obesity in older adults: a clinical overview

CM Prado, JA Batsis, LM Donini… - Nature Reviews …, 2024 - nature.com
Sarcopenic obesity is characterized by a concurrent decline in muscle mass and function,
along with increased adipose tissue. Sarcopenic obesity is a growing concern in older …

[HTML][HTML] Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR)

M Izquierdo, P de Souto Barreto, H Arai… - The Journal of nutrition …, 2025 - Elsevier
Aging, a universal and inevitable process, is characterized by a progressive accumulation of
physiological alterations and functional decline over time, leading to increased vulnerability …

Sarcopenia and diabetes: A detrimental liaison of advancing age

G Lisco, OE Disoteo, A De Tullio, V De Geronimo… - Nutrients, 2023 - mdpi.com
Sarcopenia is an age-related clinical complaint characterized by the progressive
deterioration of skeletal muscle mass and strength over time. Type 2 diabetes (T2D) is …

Bidirectional transitions of sarcopenia states in older adults: The longitudinal evidence from CHARLS

YX Luo, XH Zhou, T Heng, LL Yang… - Journal of Cachexia …, 2024 - Wiley Online Library
Background Sarcopenia, the age‐related loss of muscle mass and function, brings multiple
adverse outcomes including disability and death. Several sarcopenia consensuses have …

Advances in exercise to alleviate sarcopenia in older adults by improving mitochondrial dysfunction

Y Zhu, X Zhou, A Zhu, S Xiong, J Xie, Z Bai - Frontiers in Physiology, 2023 - frontiersin.org
Sarcopenia is a chronic degenerative disease affecting primarily older adults. A growing
aging population is gradually increasing the number of patients suffering from sarcopenia …

Nutrition in the prevention and treatment of skeletal muscle ageing and sarcopenia: A single nutrient, a whole food and a whole diet approach

A Granic, AA Sayer, R Cooper… - Proceedings of the …, 2024 - cambridge.org
Loss of skeletal muscle strength and mass (sarcopenia) is common in older adults and
associated with an increased risk of disability, frailty and premature death. Finding cost …

The effects of β-hydroxy-β-methylbutyrate or HMB-rich nutritional supplements on sarcopenia patients: a systematic review and meta-analysis

H Su, H Zhou, Y Gong, S Xiang, W Shao, X Zhao… - Frontiers in …, 2024 - frontiersin.org
Background Sarcopenia is a progressive, systemic skeletal muscle disorder. Resistance
exercise and physical activity have been proven effective in its treatment, but consensus on …

Unraveling the causes of sarcopenia: Roles of neuromuscular junction impairment and mitochondrial dysfunction

Y Miao, L Xie, J Song, X Cai, J Yang, X Ma… - Physiological …, 2024 - Wiley Online Library
Sarcopenia is a systemic skeletal muscle disease characterized by a decline in skeletal
muscle mass and function. Originally defined as an age‐associated condition, sarcopenia …

Mitigating sarcopenia with diet and exercise

A Shefflette, N Patel, J Caruso - International Journal of Environmental …, 2023 - mdpi.com
Sarcopenia is the loss of muscle mass and function from aging, inactivity, or disuse. It is a
comorbidity to numerous conditions that exacerbates their severity and adversely impacts …