Preterm birth, intrauterine infection, and fetal inflammation

MW Kemp - Frontiers in immunology, 2014 - frontiersin.org
Preterm birth (PTB)(delivery before 37 weeks' gestation) is a leading cause of neonatal
death and disease in industrialized and developing countries alike. Infection (most notably …

Computational insights into the structural dynamics of MDA5 variants associated with Aicardi–Goutières syndrome and Singleton–Merten syndrome

V Gosu, S Sasidharan, P Saudagar, HK Lee, D Shin - Biomolecules, 2021 - mdpi.com
Melanoma differentiation-associated protein 5 (MDA5) is a crucial RIG-I-like receptor RNA
helicase enzyme encoded by IFIH1 in humans. Single nucleotide polymorphisms in the …

Diversity, antimicrobial action and structure-activity relationship of buffalo cathelicidins

B Brahma, MC Patra, S Karri, M Chopra, P Mishra… - PLoS …, 2015 - journals.plos.org
Cathelicidins are an ancient class of antimicrobial peptides (AMPs) with broad spectrum
bactericidal activities. In this study, we investigated the diversity and biological activity of …

[HTML][HTML] Poly (I: C), a double stranded RNA analog, activates the anti-viral DNA sensors in buffalo fibroblasts

JS Chera, S Kumar, AK Bairagi, A Kumar, P Chandra… - Veterinary Vaccine, 2023 - Elsevier
Polyinosinic: polycytidylic acid or poly (I: C) is a double stranded RNA analog that is known
for stimulating RNA sensing pathways in a variety of cell culture and animal models …

Poly I: C stimulation in-vitro as a marker for an antiviral response in different cell types generated from Buffalo (Bubalus bubalis)

A Vats, D Gautam, J Maharana, JS Chera, S Kumar… - Molecular …, 2020 - Elsevier
The innate immune system is activated upon virus invasion of a host cell by recognizing viral
component, such as dsRNA through specific receptors, resulting in the production of type-I …

Characterization and expression profiling of buffalo IFN-lambda family

D Gautam, A Sindhu, A Vats, S Rajput… - Veterinary Immunology …, 2024 - Elsevier
Interferon lambda (IFN-λ) is an important type III interferon triggered mainly by viral infection.
IFN-λ binds to their heterodimeric receptors and signals through JAK-STAT pathways similar …

A comparative study on retinoic acid inducible gene 1 like receptors (RLR) mediated in vitro antiviral response in Indian Bakarwali and Marwari goat breeds

G Kaur, V Sharma, JA Ahmed, A Malik, A Saleem… - Gene Reports, 2023 - Elsevier
The aim of this work was to study in vitro immune response in goat fibroblasts mediated
through retinoic acid inducible gene 1 like receptors (RLRs). The primary cultures of foetal …

Comparative Genomic Analysis of Buffalo (Bubalus bubalis) NOD1 and NOD2 Receptors and Their Functional Role in In-Vitro Cellular Immune Response

B Brahma, S Kumar, BC De, P Mishra, MC Patra… - Plos one, 2015 - journals.plos.org
Nucleotide binding and oligomerization domain (NOD)-like receptors (NLRs) are innate
immune receptors that recognize bacterial cell wall components and initiate host immune …

Interactions between respiratory coinfecting pathogens in cattle: impact on pathogens evolution and respiratory disease complex severity

M Gaudino - 2022 - theses.hal.science
Bovine respiratory disease (BRD) represents a major economic obstacle for cattle farming.
BRD has multifactorial etiology, involving pathogens but also environmental and …

Facteurs de risque pour les maladies inflammatoires de l'intestin: caractérisation de l'impact de variants rares d'IFIH1 sur la réponse épithéliale antivirale

L Pruneau - 2020 - papyrus.bib.umontreal.ca
Les maladies inflammatoires de l'intestin (MII), incluant la maladie de Crohn et la colite
ulcéreuse, sont des maladies chroniques qui résultent d'un dérèglement de la réponse …