Targeted therapies and immunotherapies in the treatment of esophageal cancers

A Barsouk, P Rawla, AV Hadjinicolaou, JS Aluru… - Medical …, 2019 - mdpi.com
Esophageal cancer (EC) is among the most frequent and deadly cancers around the world.
While esophageal adenocarcinoma (EAC) has one of the fastest-growing incidences …

Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer

X Zhang, M Wang, J Feng, B Qin, C Zhang… - Journal of …, 2022 - Springer
The development of multidrug resistance (MDR) during cancer chemotherapy is a major
challenge in current cancer treatment strategies. Numerous molecular mechanisms …

Sex differences in survival following surgery for esophageal cancer: A systematic review and meta-analysis

E Liatsou, I Bellos, I Katsaros… - Diseases of the …, 2024 - academic.oup.com
The impact of sex on the prognosis of patients with esophageal cancer remains unclear.
Evidence supports that sex-based disparities in esophageal cancer survival could be …

Long noncoding RNA PVT1 promotes tumour progression via the miR-128/ZEB1 axis and predicts poor prognosis in esophageal cancer

J Hu, W Gao - Clinics and Research in Hepatology and …, 2021 - Elsevier
Purpose To confirm the value of PVT1 as a prognostic marker both in tumour tissue and
serum of patients with esophageal cancer and clarify the mechanism. Methods This study …

MiR-129-2-3p inhibits esophageal carcinoma cell proliferation, migration, and invasion via targeting DNMT3B

X Peng, X Wu, G Wu, C Peng, B Huang… - Current Molecular …, 2023 - ingentaconnect.com
Purpose: The study aims to explore the regulatory mechanism of miR-129-2-3p underlying
esophageal carcinoma (EC) cell progression and generate new ideas for targeted treatment …

MiR-139-5p regulates VEGFR and downstream signaling pathways to inhibit the development of esophageal cancer

W Jiao, J Zhang, Y Wei, J Feng, M Ma, H Zhao… - Digestive and Liver …, 2019 - Elsevier
Abstract Background MiR-139-5p plays a significant role in tumorigenesis, metastasis and
recurrence, suggesting that it may potentially be used as a promising biomarker for …

The prognostic value of lymph node ratio in locally advanced esophageal cancer patients who received neoadjuvant chemotherapy

K Kano, T Yamada, K Komori, H Watanabe… - Annals of Surgical …, 2021 - Springer
Background The lymph node (LN) ratio (LNR) has been proposed as a sensitive
prognosticator in patients with esophageal squamous cell carcinoma (ESCC), especially …

Methylation-associated silencing of miR-128 promotes the development of esophageal cancer by targeting COX-2 in areas with a high incidence of esophageal …

J Jin, T Guo, Y Guo, J Liu, F Qu… - … Journal of Oncology, 2018 - spandidos-publications.com
Esophageal cancer is one of the most common cancer types in the world, with a widely
varying incidence between different regions. Zinc deficiency (ZD) is very common in high …

Novel cancer‐specific epidermal growth factor receptor antibody obtained from the serum of esophageal cancer patients with long‐term survival

S Takagi‐Maeda, S Yajima, T Suzuki, K Usami… - Cancer …, 2022 - Wiley Online Library
Although esophageal cancer has a poor prognosis after recurrence, some patients have
shown long‐term survival despite recurrence. We hypothesized that induction of either …

Long Non-coding RNA X-Inactive Specific Transcript Promotes Esophageal Squamous Cell Carcinoma Progression via the MicroRNA 34a/Zinc Finger E-box–Binding …

B Guo, M He, M Ma, Z Tian, J Jin, G Tian - Digestive Diseases and …, 2024 - Springer
Background The long non-coding RNA X-inactive specific transcript (XIST) plays a crucial
role in transcriptional silencing of the X chromosome. Zinc finger E-box-binding homeobox 1 …