Resveratrol (3, 5, 4′-trihydroxystilbene; RSV) is a natural nonflavonoid polyphenol present
in many species of plants, particularly in grapes, blueberries, and peanuts. Several in vitro …

Ovarian cancer is still the deadliest of all gynecologic malignancies in women worldwide.
This is attributed to two main features of these tumors, namely,(i) a diagnosis at an advanced …

Thirteen common susceptibility loci have been reproducibly associated with cutaneous
malignant melanoma (CMM). We report the results of an international 2-stage meta-analysis …

Abstract The cytochrome P450 (P450) enzymes first attracted interest because of their
relevance to the metabolism of drugs, steroids, and carcinogens. Collectively, the 57 human …

Human cytochrome P450 enzymes (CYPs) play a critical role in various biological
processes and human diseases. CYP1 family members, including CYP1A1, CYP1A2, and …

Significance: Targeted cancer therapy with minimal off-target consequences has shown
promise for some cancer types. Although cytochrome P450 (CYP) consists of 18 families …

Breast cancer progression including bone metastasis is a complex process involving
numerous changes in gene expression and function. MicroRNAs (miRNAs) are small …

Cancer chemoprevention is the use of synthetic, natural or biological agents to prevent or
delay the development or progression of malignancies. Intriguingly, many phytochemicals …

Cytochrome P450 1B1 (CYP1B1) is induced during the early stage of cancer and is
universally overexpressed in tumors. Thus, it was considered as a potential biomarker for …

Background Chemoresistance contributes to treatment failure of gastric cancer (GC) patients
but the molecular mechanism of chemoresistance in GC is still unclear. Long-chain …