The interstitial pneumonias comprise a diverse group of diseases that are typically defined
by their cause (either idiopathic or non-idiopathic) and their distinct histopathological …

SSc is a highly heterogeneous autoimmune disease typified by varying clinical trajectories.
Its management may be stratified within the first five years by subclassifying patients based …

Compromised regenerative capacity of lung epithelial cells can lead to cellular senescence,
which may precipitate fibrosis. While increased markers of senescence have been reported …

Objective Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is characterized
by variable clinical outcomes, activation of innate immune pattern‐recognition receptors …

Interstitial lung disease (ILD) may occur in patients with a rheumatic autoimmune disease
(AD), increasing their risk of morbidity and mortality. However, little is known about the …

Objectives To establish a framework by which experts define disease subsets in systemic
sclerosis associated interstitial lung disease (SSc-ILD). Methods A conceptual framework for …

Interstitial lung disease (ILD) is a frequent manifestation of connective tissue diseases
(CTDs), with incidence and prevalence variously assessed in the literature but reported in …

Abstract Objective The Outcome Measures in Rheumatology (OMERACT) is a research
organization focused on improving health care outcomes for patients with autoimmune and …

Systemic sclerosis is a complex, multi-organ disease which causes substantial and
progressive symptoms and impairs quality of life. International guidelines recommend early …

Background Interstitial lung disease (ILD) is highly prevalent in patients with connective
tissue disease (CTD) and is poorly characterised in South Africa. Objective To describe the …