It is well known that C-peptide fulfills an important function in the synthesis of insulin. After
cleavage of proinsulin in the pancreatic b-cells, the 31-amino acid C-peptide is secreted into …

Diabetes mellitus (DM) is a complex metabolic disease affecting one-third of the United
States population. It is characterized by hyperglycemia, where the hormone insulin is either …

Objectives Angiographic high thrombus burden (HTB) is associated with increased adverse
cardiovascular events in patients with ST-elevation myocardial infarction (STEMI). HbA1c …

C‐peptide, a byproduct of insulin synthesis believed to be biologically inert, is emerging as a
multifunctional molecule. C‐peptide serves an anti‐inflammatory and anti‐atherogenic role …

People with type 1 diabetes (T1D) must administer insulin exogenously due to the
destruction of their pancreatic β-cells. Endogenous insulin is stored in β-cell granules along …

ATP release from erythrocytes in response to reduced oxygen (O2) tension stimulates local
vasodilation, enabling these cells to direct perfusion to areas in skeletal muscle in need of …

C‐peptide is a cleavage product of proinsulin that acts on different type of cells, such as
blood and endothelial cells. C‐peptide biological effects may be different in type 1 and type …

Heavy metals are common marine and soil pollutants that are mainly the result of industrial
activity, and are a threat to the environment and human health. In this study, 1H nuclear …

Background C‐peptide has been shown to stimulate the production of nitric oxide (NO) in
aortic endothelial cells via activation of endothelial nitric oxide synthase (eNOS) through an …

Erythrocytes participate in the matching of oxygen (O2) delivery with local need in skeletal
muscle via the release of O2 and the vasodilator, ATP. It was reported that a concentration of …