Allergic diseases: a comprehensive review on risk factors, immunological mechanisms, link with COVID-19, potential treatments, and role of allergen bioinformatics

FM Aldakheel - International Journal of Environmental Research and …, 2021 - mdpi.com
The prevalence of allergic diseases is regarded as one of the key challenges in health
worldwide. Although the precise mechanisms underlying this rapid increase in prevalence …

Biomedical applications of ion-doped bioactive glass: A review

MB Taye - Applied Nanoscience, 2022 - Springer
Bioactive glasses (BG) have been used in biomedical (dental applications or bone graft
replacement for bone healing) and technological applications, and researchers have …

Potent antibiotic design via guided search from antibacterial activity evaluations

L Chen, L Yu, L Gao - Bioinformatics, 2023 - academic.oup.com
Motivation The emergence of drug-resistant bacteria makes the discovery of new antibiotics
an urgent issue, but finding new molecules with the desired antibacterial activity is an …

An integrative reverse vaccinology, immunoinformatic, docking and simulation approaches towards designing of multi-epitopes based vaccine against monkeypox …

A Ullah, FA Shahid, MU Haq… - Journal of …, 2023 - Taylor & Francis
Monkeypox is a viral zoonotic disease that is caused by the monkeypox virus (MPXV) and is
mainly transmitted to human through close contact with an infected person, animal, or …

Designing of a Recombinant Multi-Epitopes Based Vaccine against Enterococcus mundtii Using Bioinformatics and Immunoinformatics Approaches

M Alharbi, A Alshammari, AF Alasmari… - International journal of …, 2022 - mdpi.com
Enterococcus species are an emerging group of bacterial pathogens that have a significant
role in hospital-associated infections and are associated with higher mortality and morbidity …

Multi-epitope vaccine design against monkeypox virus via reverse vaccinology method exploiting immunoinformatic and bioinformatic approaches

K Bhattacharya, IM Shamkh, MS Khan, MM Lotfy… - Vaccines, 2022 - mdpi.com
(1) Background: The monkeypox virus is a zoonotic orthopox DNA virus that is closely linked
to the virus. In light of the growing concern about this virus, the current research set out to …

Towards A Novel Multi-Epitopes Chimeric Vaccine for Simulating Strong Immune Responses and Protection against Morganella morganii

A Ullah, S Ahmad, S Ismail, Z Afsheen… - International Journal of …, 2021 - mdpi.com
Morganella morganii is one of the main etiological agents of hospital-acquired infections
and no licensed vaccine is available against the pathogen. Herein, we designed a multi …

Designing of a Novel Multi-Antigenic Epitope-Based Vaccine against E. hormaechei: An Intergraded Reverse Vaccinology and Immunoinformatics Approach

TH Albekairi, A Alshammari, M Alharbi, AF Alshammary… - Vaccines, 2022 - mdpi.com
Enterobacter hormaechei is involved in multiple hospital-associated infections and is
resistant to beta-lactam and tetracycline antibiotics. Due to emerging antibiotics resistance in …

Computer-Aided Multi-Epitope Vaccine Design against Enterobacter xiangfangensis

A Alshammari, M Alharbi, A Alghamdi… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance is a global public health threat and is associated with high mortality due
to antibiotics' inability to treat bacterial infections. Enterobacter xiangfangensis is an …

[HTML][HTML] Genome-level therapeutic targets identification and chimeric Vaccine designing against the Blastomyces dermatitidis

S Mursaleen, A Sarfraz, M Shehroz, A Zaman… - Heliyon, 2024 - cell.com
Blastomyces dermatitidis is a thermally dimorphic fungus that can cause serious and
sometimes fatal infections, including blastomycosis. After spore inhalation, a pulmonary …