Cardiac surgery-associated acute kidney injury: risk factors, pathophysiology and treatment

Y Wang, R Bellomo - Nature Reviews Nephrology, 2017 - nature.com
Cardiac surgery-associated acute kidney injury (CSA-AKI) is the most common clinically
important complication in adult patients undergoing open heart surgery, and is associated …

Acute kidney injury after cardiac surgery: prediction, prevention, and management

SR Cheruku, J Raphael, JA Neyra, AA Fox - Anesthesiology, 2023 - ingentaconnect.com
Acute kidney injury (AKI) is a common complication in cardiac surgery patients, with a
reported incidence of 20 to 30%. The development of AKI is associated with worse short-and …

Biomarkers of acute and chronic kidney disease

WR Zhang, CR Parikh - Annual review of physiology, 2019 - annualreviews.org
The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …

[PDF][PDF] Acute kidney injury—epidemiology, outcomes and economics

O Rewa, SM Bagshaw - Nature reviews nephrology, 2014 - nature.com
Acute kidney injury (AKI) is a widespread problem of epidemic status. Compelling evidence
indicates that the incidence of AKI is rapidly increasing, particularly among hospitalized …

Biomarkers of drug-induced kidney toxicity

BR Griffin, S Faubel, CL Edelstein - Therapeutic drug monitoring, 2019 - journals.lww.com
Blood urea nitrogen and serum creatinine are imperfect markers of kidney function because
they are influenced by many renal and nonrenal factors independent of kidney function. A …

Management of patients at risk of acute kidney injury

J Vanmassenhove, J Kielstein, A Jörres, W Van Biesen - The lancet, 2017 - thelancet.com
Acute kidney injury (AKI) is a multifaceted syndrome that occurs in different settings. The
course of AKI can be variable, from single hit and complete recovery, to multiple hits …

Biomarkers of AKI: a review of mechanistic relevance and potential therapeutic implications

JL Alge, JM Arthur - Clinical Journal of the American Society of …, 2015 - journals.lww.com
AKI is a common clinical condition associated with a number of adverse outcomes. More
timely diagnosis would allow for earlier intervention and could improve patient outcomes …

Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature

J Vanmassenhove, R Vanholder… - Nephrology Dialysis …, 2013 - academic.oup.com
Background Acute kidney injury (AKI) remains associated with high morbidity and mortality,
despite progress in medical care. Although the RIFLE (Risk, Injury, Failure, Loss, End-Stage …

Developing a neonatal acute kidney injury research definition: a report from the NIDDK neonatal AKI workshop

M Zappitelli, N Ambalavanan, DJ Askenazi… - Pediatric …, 2017 - nature.com
Critically ill patients are at highest risk for acute kidney injury (AKI), or abrupt renal
dysfunction. Before 2004, most pediatric AKI literature reported on the technical feasibility …

Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current status

A Haase-Fielitz, M Haase… - Annals of clinical …, 2014 - journals.sagepub.com
Background The early prediction of acute kidney injury (AKI) by current clinical and
laboratory methods remains inadequate. Neutrophil gelatinase-associated lipocalin (NGAL) …