Trehalose: current use and future applications

S Ohtake, YJ Wang - Journal of pharmaceutical sciences, 2011 - Elsevier
Trehalose, a disaccharide of glucose, has been reported to accumulate in many organisms
that can withstand extended periods of inanimation. Since this discovery, the properties of …

An overview of liposome lyophilization and its future potential

C Chen, D Han, C Cai, X Tang - Journal of controlled release, 2010 - Elsevier
Lyophilization is a promising approach to ensure the long-term stability of liposomes. After
decades of studies in this field, different lyoprotective mechanisms, such as water …

Plant fructans in stress environments: emerging concepts and future prospects

R Valluru, W Van den Ende - Journal of experimental botany, 2008 - academic.oup.com
Plants are sessile and sensitive organisms known to possess various regulatory
mechanisms for defending themselves under stress environments. Fructans are fructose …

Trehalose as a “chemical chaperone” fact and fantasy

JH Crowe - Molecular aspects of the stress response: chaperones …, 2007 - Springer
Trehalose is a disaccharide of glucose that is found at high concentrations in a wide variety
of organisms that naturally survive drying in nature. Many years ago we reported that this …

Antifungal properties of phosphatidylcholine-oleic acid liposomes encapsulating garlic against environmental fungal in wheat bread

CMB Pinilla, RCS Thys, A Brandelli - International Journal of Food …, 2019 - Elsevier
Liposomes have gained great interest in the food and pharmaceutical industry as colloidal
carriers of bioactive compounds. In this work, liposomes of phosphatidylcholine (PC) and …

Lyophilized liposome-based parenteral drug development: Reviewing complex product design strategies and current regulatory environments

Y Wang, DW Grainger - Advanced drug delivery reviews, 2019 - Elsevier
Given the successful entry of several liposomal drug products into market, and some with
decades of clinical efficacy, liposomal drug delivery systems have proven capabilities to …

Trehalose renders the dauer larva of Caenorhabditis elegans resistant to extreme desiccation

C Erkut, S Penkov, H Khesbak, D Vorkel, JM Verbavatz… - Current Biology, 2011 - cell.com
Water is essential for life on Earth. In its absence, however, some organisms can interrupt
their life cycle and temporarily enter an ametabolic state, known as anhydrobiosis [1]. It is …

[HTML][HTML] Interaction of the disaccharide trehalose with a phospholipid bilayer: a molecular dynamics study

CS Pereira, RD Lins, I Chandrasekhar, LCG Freitas… - Biophysical journal, 2004 - cell.com
The disaccharide trehalose is well known for its bioprotective properties. Produced in large
amounts during stress periods in the life of organisms able to survive potentially damaging …

Role of trehalose in heat and desiccation tolerance in the soil bacterium Rhizobium etli

M Reina-Bueno, M Argandoña, JJ Nieto… - BMC microbiology, 2012 - Springer
Background The compatible solute trehalose is involved in the osmostress response of
Rhizobium etli, the microsymbiont of Phaseolus vulgaris. In this work, we reconstructed …

Improving the thermal stability of natural bioactive ingredients via encapsulation technology

S Bodbodak, M Nejatian… - Critical Reviews in …, 2024 - Taylor & Francis
Bioactive compounds (bioactives) such as phenolic acids, coumarins, flavonoids, lignans
and carotenoids have a marked improvement effect on human health by acting on body …