Immunomodulation effect of biomaterials on bone formation

T Zhao, Z Chu, J Ma, L Ouyang - Journal of Functional Biomaterials, 2022 - mdpi.com
Traditional bone replacement materials have been developed with the goal of directing the
osteogenesis of osteoblastic cell lines toward differentiation and therefore achieving …

Immunomodulatory Biomaterials: Tailoring Surface Properties to Mitigate Foreign Body Reaction and Enhance Tissue Regeneration

H Amani, M Alipour, E Shahriari… - Advanced Healthcare …, 2024 - Wiley Online Library
The immune cells have demonstrated the ability to promote tissue repair by removing debris,
breaking down the extracellular matrix, and regulating cytokine secretion profile. If the …

A thrombin-triggered self-regulating anticoagulant strategy combined with anti-inflammatory capacity for blood-contacting implants

Y Wang, H Wu, Z Zhou, MF Maitz, K Liu, B Zhang… - Science …, 2022 - science.org
Interrelated coagulation and inflammation are impediments to endothelialization, a
prerequisite for the long-term function of cardiovascular materials. Here, we proposed a self …

High-performance implantable bioelectrodes with immunocompatible topography for modulation of macrophage responses

S Lee, J Park, S Kim, J Ok, JI Yoo, YS Kim, Y Ahn… - ACS …, 2022 - ACS Publications
Implantable bioelectrodes enable precise recording or stimulation of electrical signals with
living tissues in close contact. However, their performance is frequently compromised owing …

The role of surface chemistry in the osseointegration of PEEK implants

E Buck, S Lee, Q Gao, SD Tran, F Tamimi… - ACS Biomaterials …, 2022 - ACS Publications
Poly (etheretherketone)(PEEK) implants suffer from poor osseointegration because of
chronic inflammation. In this study, we hypothesized that adding NH2 and COOH groups to …

Poly-Ether-Ether-Ketone (PEEK) Biomaterials and Composites: Challenges, Progress, and Opportunities

J Molinar-Díaz, AJ Parsons, I Ahmed, NA Warrior… - Polymer …, 2024 - Taylor & Francis
Polyetheretherketone (PEEK) is a lightweight, bioinert, high-performance thermoplastic that
is beginning to see clinical use in orthopedic applications. PEEK outperforms conventional …

Sperm activate TLR2/TLR1 heterodimerization to induce a weak proinflammatory response in the bovine uterus

A Mansouri, MS Yousef, R Kowsar, N Usui… - Frontiers in …, 2023 - frontiersin.org
Toll-like receptor 2 (TLR2) signaling pathway is involved in the sperm-triggered uterine
inflammatory response at insemination, but its precise mechanism at molecular-level …

[HTML][HTML] Latest advances: Improving the anti-inflammatory and immunomodulatory properties of PEEK materials

Z Zhang, X Zhang, Z Zheng, J Xin, S Han, J Qi… - Materials Today Bio, 2023 - Elsevier
Excellent biocompatibility, mechanical properties, chemical stability, and elastic modulus
close to bone tissue make polyetheretherketone (PEEK) a promising orthopedic implant …

[HTML][HTML] Unraveling the role of carboxylate groups and elastin particle size in medial calcification

T Song, M Cerruti - International Journal of Biological Macromolecules, 2024 - Elsevier
While it is known that calcium phosphate (CaP) minerals deposit in elastin-rich medial layers
of arteries during medial calcification, their nucleation and growth sites are still debated …

Potential effects of biomaterials on macrophage function and their signalling pathways

F Zhu, S Wang, X Zhu, C Pang, P Cui, F Yang… - Biomaterials …, 2023 - pubs.rsc.org
The use of biomaterials in biomedicine and healthcare has increased in recent years.
Macrophages are the primary immune cells that induce inflammation and tissue repair after …