Macroautophagy (hereafter called autophagy) is a highly conserved physiological process
that degrades over-abundant or damaged organelles, large protein aggregates and …

Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Biomarker discovery and implementation are at the forefront of the precision medicine
movement. Modern advances in the field of metabolomics afford the opportunity to readily …

Autophagy and the ubiquitin–proteasome system (UPS) are the two major intracellular
quality control and recycling mechanisms that are responsible for cellular homeostasis in …

In mammalian cells, two cellular organelles, mitochondria and peroxisomes, share the ability
to degrade fatty acid chains. Although each organelle harbors its own fatty acid β-oxidation …

Here, we report a β-galactosidase (β-Gal)-responsive photochromic fluorescent probe, NpG,
that was designed to prebind to human serum albumin (HSA) to form the probe/protein …

Autophagy is a major degradation pathway that utilizes lysosome hydrolases to degrade
cellular constituents and is often induced under cellular stress conditions to restore cell …

Mitochondrial network remodeling between fused and fragmented states facilitates
mitophagy, interaction with other organelles, and metabolic flexibility. Aging is associated …

OBJECTIVE Nonalcoholic fatty liver disease (NAFLD) is a liver phenotype of type 2 diabetes
and obesity. Currently, the efficacy of sodium–glucose cotransporter 2 (SGLT2) inhibitors …

Over the past decades, peroxisomes have emerged as key regulators in overall cellular lipid
and reactive oxygen species metabolism. In mammals, these organelles have also been …