FPGA implementation of a data-driven stochastic biochemical simulator with the next reaction method

M Yoshimi, Y Iwaoka, Y Nishikawa… - … Conference on Field …, 2007 - ieeexplore.ieee.org
This paper introduces a scalable FPGA implementation of a stochastic simulation algorithm
(SSA) called the Next Reaction Method. There are some hardware approaches of SSAs that …

Python to accelerate embedded SoC design: A case study for systems biology

E Logaras, OG Hazapis, ES Manolakos - ACM Transactions on …, 2014 - dl.acm.org
We present SysPy (System Python) a tool which exploits the strengths of the popular Python
scripting language to boost design productivity of embedded System on Chips for FPGAs …

Scalable FRM-SSA SoC design for the simulation of networks with thousands of biochemical reactions in real time

OG Hazapis, ES Manolakos - 2011 21st International …, 2011 - ieeexplore.ieee.org
Simulation of biomolecular networks with thousands of reactions is becoming essential for
systems biology. We are presenting the design of a scalable System on Chip parallel …

Fpga-based hprc for bioinformatics applications

Y Yamaguchi, Y Osana, M Yoshimi… - … computing using FPGAs, 2013 - Springer
Bioinformatics is one of the most frequently applied fields in FPGAs. Some applications in
this field can be efficiently implemented by systolic arrays, which are intrinsically suited to …

Scalable FPGA accelerator of the NRM algorithm for efficient stochastic simulation of large-scale biochemical reaction networks

E Koutsouradis, G Provelengios… - … on Digital System …, 2015 - ieeexplore.ieee.org
Stochastic simulation of large-scale biochemical reaction networks, with thousands of
reactions, is important for systems biology and medicine since it will enable the insilico …

Low-power design strategies for mobile computing

A Prasad, J Mathews, N Naganathan - 19th International Conference …, 2006 - computer.org
Stochastic simulation of large-scale biochemical reaction networks, with thousands of
reactions, is important for systems biology and medicine since it will enable the insilico …

A framework for implementing a network-based stochastic biochemical simulator on an fpga

M Yoshimi, Y Nishikawa, T Kojima… - … Conference on Field …, 2007 - ieeexplore.ieee.org
This paper studies several designs of network-based FPGA implementation of a stochastic
simulation algorithm called the next reaction method, known for its large number of …

Toward a fast stochastic simulation processor for biochemical reaction networks

H Park, A Gerstlauer - 2013 IEEE 24th International Conference …, 2013 - ieeexplore.ieee.org
Computational studies of biological systems have gained widespread attention as a
promising alternative to regular experimentation. Within this domain, stochastic simulation …

A soft IP core generating SoCs for the efficient stochastic simulation of large Biomolecular Networks using FPGAs

OG Hazapis, E Logaras… - 2012 19th IEEE …, 2012 - ieeexplore.ieee.org
A soft IP core, expressed in parametric VHDL, has been developed and used to synthesize
different multiprocessor Systems on Chip (SoCs) for the stochastic simulation of large-size …

[PDF][PDF] Algorithm/Architecture Co-Design of a Stochastic Simulation System-on-Chip

H Park, X Shen, H Vikalo, A Gerstlauer - 2011 - researchgate.net
Computational models of gene regulatory networks (GRNs) well describe the behavior of
interactions among molecular species over time. For larger networks, the problem of state …