The leukotriene receptor antagonist montelukast as a potential COVID-19 therapeutic

L Aigner, F Pietrantonio… - Frontiers in molecular …, 2020 - frontiersin.org
The emergence and global impact of COVID-19 has focused the scientific and medical
community on the pivotal influential role of respiratory viruses as causes of severe …

Asthma pharmacotherapy: an update on leukotriene treatments

HKT Trinh, SH Lee, TBT Cao… - Expert review of respiratory …, 2019 - Taylor & Francis
Introduction: Asthma is a chronic inflammatory disease of the airways with a large
heterogeneity of clinical phenotypes. There has been increasing interest regarding the role …

[HTML][HTML] Fractional Exhaled Nitric Oxide (FENO) in the management of asthma: a position paper of the Italian Respiratory Society (SIP/IRS) and Italian Society of …

E Heffler, GE Carpagnano, E Favero… - Multidisciplinary …, 2020 - ncbi.nlm.nih.gov
Asthma prevalence in Italy is on the rise and is estimated to be over 6% of the general
population. The diagnosis of asthma can be challenging and elusive, especially in children …

Factors Influencing the Concentration of Exhaled Nitric Oxide (FeNO) in School Children Aged 8–9-Years-Old in Krakow, with High FeNO Values≥ 20 ppb

M Czubaj-Kowal, GJ Nowicki, R Kurzawa, M Polak… - Medicina, 2022 - mdpi.com
Background and Objectives: Measurement of fractional exhaled nitric oxide (FeNO)
concentration is currently used as a non-invasive biomarker to assess airway inflammation …

Antileukotrienes improve naso‐ocular symptoms and biomarkers in patients with NARES and asthma

E De Corso, R Anzivino, J Galli, S Baroni… - The …, 2019 - Wiley Online Library
Objective The aim of our study was to analyze the montelukast effectiveness in improving
oculonasal symptoms, patient‐reported outcomes (PROs), and eosinophilic biomarkers in …

[HTML][HTML] lncRNA PCGEM1 strengthens anti-inflammatory and lung protective effects of montelukast sodium in children with cough-variant asthma

Z Xu, L Meng, Y Xie, W Guo - Brazilian Journal of Medical and …, 2020 - SciELO Brasil
Montelukast sodium is an effective and well-tolerated anti-asthmatic drug. Long non-coding
RNAs (lncRNAs) are involved in the treatment of asthma. Therefore, this study aimed to …

Sleep-disordered breathing in children with recurrent wheeze/asthma: a single centre study

M Zaffanello, E Gasperi, L Tenero, M Piazza… - Children, 2017 - mdpi.com
The relationship between asthma and sleep-disordered breathing is bidirectional due to
common risk factors that promote airway inflammation. Obstructive sleep-disordered …

[HTML][HTML] 白三烯受体拮抗剂通过Wnt/β-catenin 信号通路影响哮喘小鼠气道重塑机制的研究

蒋昱, 黄传君, 李泽, 张才擎 - 中国医科大学学报, 2018 - html.rhhz.net
目的探讨白三烯受体拮抗剂影响Wnt7b, β-catenin 及c-Myc 表达, 干预哮喘小鼠气道重塑机制的
研究. 方法采用卵蛋白(OVA) 致敏和激发建立小鼠哮喘模型. 将小鼠分为对照组 …

Preformulation studies of the γ-cyclodextrin and montelukast inclusion compound prepared by comilling

JS Barbosa, MM Nolasco, P Ribeiro-Claro… - Journal of …, 2019 - Elsevier
Montelukast (MLK), an oral antiasthmatic drug with growing use, requires special care in
formulation and storage to avoid its degradation by action of light and water. This work …

Pediatric Asthma: Where Has Montelukast Gone?

M Maglione, A Giannattasio, A Pascarella, V Tipo - Applied Sciences, 2023 - mdpi.com
At its introduction in the management of pediatric asthma, montelukast was regarded as a
potentially revolutionary drug due to its mechanism of action and easy clinical applicability …