Association Between AIRE Polymorphisms rs870881 (C> T), rs1003854 (T> C) and Rheumatoid Arthritis Risk: A Hungarian Case-control Study

B Berczi, N Nusser, I Peter, B Nemeth, Z Gyongyi - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: Autoimmune regulator (AIRE) is a transcription factor that plays pivotal role
in controlling autoimmunity. In the thymus, it supports the presentation of peripheral tissue …

Association of AIRE (rs2075876), but not CTLA4 (rs231775) polymorphisms with systemic lupus erythematosus

SA Alghamdi, SW Kattan, EA Toraih, MG Alrowaili… - Gene, 2021 - Elsevier
Background The AIRE (rs2075876) and CTLA4 (rs231775) variants have a crucial function
in controlling the negative selection and suppression of T lymphocytes. Numerous reports …

Autoimmune Regulator Gene Polymorphisms and the Risk of Primary Immune Thrombocytopenic Purpura: A Case-Control Study

MT Abdel Ghafar, OA Elshora, AA Allam… - International Journal of …, 2023 - mdpi.com
This study aimed to assess the possible association between two single nucleotide
polymorphisms (SNPs) of the autoimmune regulator (AIRE) gene (rs2075876 G/A and …

Role of Autoimmune Regulator Protein (AIRE-P) in the Pathophysiology of Autism Spectrum Disorder (ASD) in Saudi Children

HA Al-Ghabban, LY Al-Ayadhi - Archives of Pharmacy Practice, 2023 - archivepp.com
Numerous studies show the significance of immunological deficits, abnormal cytokine and
immune cell production, and autism. Through the use of the childhood autism rating scale …