Gene editing in common cardiovascular diseases

AM Lauerer, XM Caravia, LS Maier, F Chemello… - Pharmacology & …, 2024 - Elsevier
Cardiovascular diseases are the leading cause of morbidity and mortality worldwide,
highlighting the high socioeconomic impact. Current treatment strategies like compound …

[HTML][HTML] Unveiling the Spectrum of Minor Genes in Cardiomyopathies: A Narrative Review

C Micolonghi, F Perrone, M Fabiani, S Caroselli… - International Journal of …, 2024 - mdpi.com
Hereditary cardiomyopathies (CMPs), including arrhythmogenic cardiomyopathy (ACM),
dilated cardiomyopathy (DCM), and hypertrophic cardiomyopathy (HCM), represent a group …

[HTML][HTML] Hypertrophic Cardiomyopathy with Special Focus on Mavacamten and Its Future in Cardiology

E Młynarska, E Radzioch, B Dąbek, K Leszto… - Biomedicines, 2024 - mdpi.com
Hypertrophic cardiomyopathy (HCM) is a heterogeneous group of heart muscle disorders
that affects millions, with an incidence from 1 in 500 to 1 in 200. Factors such as genetics …

Identification and validation of autophagy‑related genes in hypertrophic cardiomyopathy

RB Qiu, ST Zhao, ZW Li, RY Zeng… - Experimental and …, 2024 - spandidos-publications.com
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant cardiac disorder
characterized by ventricular hypertrophy resulting from the disordered arrangement of …

[HTML][HTML] Unraveling the Genetic Heartbeat: Decoding Cardiac Involvement in Duchenne Muscular Dystrophy

V Novelli, F Canonico, R Laborante, M Manzoni… - Biomedicines, 2025 - mdpi.com
Cardiomyopathy represents the most important life-limiting condition of Duchenne muscular
dystrophy (DMD) patients after the age of 20. Genetic alterations in the DMD gene result in …

[HTML][HTML] Identifying the Pathogenic Variants in Heart Genes in Vietnamese Sudden Unexplained Death Victims by Next-Generation Sequencing

T Nguyen Tat, NTK Lien, H Luu Sy, T Ta Van… - Diagnostics, 2024 - mdpi.com
In forensics, one-third of sudden deaths remain unexplained after a forensic autopsy. A
majority of these sudden unexplained deaths (SUDs) are considered to be caused by …

ГИПЕРТРОФИЧЕСКАЯ КАРДИОМИОПАТИЯ: СОВРЕМЕННЫЕ ПОДХОДЫ К ДИАГНОСТИКЕ И ЛЕЧЕНИЮ

ЕС Енисеева - Байкальский медицинский журнал, 2024 - bmjour.ru
Аннотация В обзоре представлены данные литературы последних лет о
распространенности, этиологии, роли мутаций генов саркомера в патогенезе …