Ascorbic acid: chemistry, biology and the treatment of cancer

J Du, JJ Cullen, GR Buettner - … et Biophysica Acta (BBA)-Reviews on …, 2012 - Elsevier
Since the discovery of vitamin C, the number of its known biological functions is continually
expanding. Both the names ascorbic acid and vitamin C reflect its antiscorbutic properties …

Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways

K Huynh, BC Bernardo, JR McMullen… - Pharmacology & …, 2014 - Elsevier
Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

Antioxidant and antidiabetic effects of flavonoids: A structure‐activity relationship based study

MN Sarian, QU Ahmed, SZ Mat So'ad… - BioMed research …, 2017 - Wiley Online Library
The best described pharmacological property of flavonoids is their capacity to act as potent
antioxidant that has been reported to play an important role in the alleviation of diabetes …

Plant L‐ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing

MW Davey, MV Montagu, D Inze… - Journal of the …, 2000 - Wiley Online Library
Humans are unable to synthesise l‐ascorbic acid (L‐AA, ascorbate, vitamin C), and are thus
entirely dependent upon dietary sources to meet needs. In both plant and animal …

Oxidative stress and diabetic vascular complications.

D Giugliano, A Ceriello, G Paolisso - Diabetes care, 1996 - europepmc.org
A comment on this article appears in" Increased hydrogen peroxide formation in
polymorphonuclear leukocytes of IDDM patients." Diabetes Care. 1998 Feb; 21 (2): 326-7. A …

Oxidative stress in the pathogenesis of diabetic neuropathy

AM Vincent, JW Russell, P Low… - Endocrine …, 2004 - academic.oup.com
Oxidative stress results from a cell or tissue failing to detoxify the free radicals that are
produced during metabolic activity. Diabetes is characterized by chronic hyperglycemia that …

The role of oxidative stress in the onset and progression of diabetes and its complications: asummary of a Congress Series sponsored byUNESCO‐MCBN, the …

P Rösen, PP Nawroth, G King, W Möller… - Diabetes/metabolism …, 2001 - Wiley Online Library
This review summarises the results and discussions of an UNESCO‐MCBN supported
symposium on oxidative stress and its role in the onset and progression of diabetes. There is …

Oxidative stress and glycemic regulation

A Ceriello - Metabolism, 2000 - Elsevier
Oxidative stress is an acknowledged pathogenetic mechanism in diabetic complications.
Hyperglycemia is a widely known cause of enhanced free radical concentration, whereas …

Vitamin C supplementation for diabetes management: A comprehensive narrative review

SA Mason, L Parker, P van der Pligt… - Free Radical Biology and …, 2023 - Elsevier
Growing evidence suggests that vitamin C supplementation may be an effective adjunct
therapy in the management of people with diabetes. This paper critically reviews the current …

Dietary factors determining diabetes and impaired glucose tolerance: a 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study

EJ Feskens, SM Virtanen, L Räsänen… - Diabetes …, 1995 - Am Diabetes Assoc
OBJECTIVE To investigate the role of diet as a predictor of glucose intolerance and non-
insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS At the …