Anticoagulants: a short history, their mechanism of action, pharmacology, and indications

M Heestermans, G Poenou, H Hamzeh-Cognasse… - Cells, 2022 - mdpi.com
Anticoagulant drugs antagonize coagulation and are used to prevent or cure (recurrent)
venous thromboembolism (VTE). Drugs to prevent clotting have been used for more than a …

Acute pulmonary embolism

VF Tapson - New England Journal of Medicine, 2008 - Mass Medical Soc
Acute pulmonary embolism may occur rapidly and unpredictably and may be difficult to
diagnose. Treatment can reduce mortality, and appropriate primary prophylaxis is usually …

Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians evidence-based clinical practice …

C Kearon, EA Akl, AJ Comerota, P Prandoni… - Chest, 2012 - Elsevier
Background This article addresses the treatment of VTE disease. Methods We generated
strong (Grade 1) and weak (Grade 2) recommendations based on high-quality (Grade A) …

Trends in the management and outcomes of acute pulmonary embolism: analysis from the RIETE registry

D Jiménez, J de Miguel-Díez, R Guijarro… - Journal of the American …, 2016 - jacc.org
Background: Despite advances in hospital management in recent years, it is not clear
whether mortality after acute pulmonary embolism (PE) has decreased over time. Objectives …

Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer

AYY Lee, MN Levine, RI Baker… - New England journal …, 2003 - Mass Medical Soc
Background Patients with cancer have a substantial risk of recurrent thrombosis despite the
use of oral anticoagulant therapy. We compared the efficacy of a low-molecular-weight …

Guidance for the treatment and prevention of obstetric-associated venous thromboembolism

SM Bates, S Middeldorp, M Rodger, AH James… - Journal of thrombosis …, 2016 - Springer
Venous thromboembolism (VTE), which may manifest as pulmonary embolism (PE) or deep
vein thrombosis (DVT), is a serious and potentially fatal condition. Treatment and prevention …

Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis

P Prandoni, AWA Lensing, A Piccioli… - Blood, The Journal …, 2002 - ashpublications.org
A small proportion of patients with deep vein thrombosis develop recurrent venous
thromboembolic complications or bleeding during anticoagulant treatment. These …

Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism

V Pengo, AWA Lensing, MH Prins… - … England Journal of …, 2004 - Mass Medical Soc
Background Chronic thromboembolic pulmonary hypertension (CTPH) is associated with
considerable morbidity and mortality. Its incidence after pulmonary embolism and …

Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians evidence-based clinical practice guidelines

C Kearon, SR Kahn, G Agnelli, S Goldhaber… - Chest, 2008 - Elsevier
This chapter about treatment for venous thromboembolic disease is part of the American
College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition) …

[HTML][HTML] Incidence and mortality of venous thrombosis: a population‐based study

IA Næss, SC Christiansen, P Romundstad… - Journal of thrombosis …, 2007 - Elsevier
Background: Estimates of the incidence of venous thrombosis (VT) vary, and data on
mortality are limited. Objectives: We estimated the incidence and mortality of a first VT event …