Self-assembling nucleic acid nanostructures functionalized with aptamers

A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Functionalized DNA nanostructures for bioimaging

S Shaikh, M Younis, L Yuan - Coordination Chemistry Reviews, 2022 - Elsevier
The excellent molecular recognition, programmable and biocompatible properties make
deoxyribonucleic acid (DNA) a kind of material widely used in biomedical field. DNA …

Hollow magnetic-fluorescent nanoparticles for dual-modality virus detection

AB Ganganboina, AD Chowdhury, IM Khoris… - Biosensors and …, 2020 - Elsevier
Combination of magnetic nanomaterials with multifunctionality is an emerging class of
materials that exhibit tremendous potential in advanced applications. Synthesizing such …

Nucleic acid nanostructures for in vivo applications: The influence of morphology on biological fate

NI Langlois, KY Ma, HA Clark - Applied Physics Reviews, 2023 - pubs.aip.org
The development of programmable biomaterials for use in nanofabrication represents a
major advance for the future of biomedicine and diagnostics. Recent advances in structural …

Aptamer-functionalized nucleic acid nanotechnology for biosensing, bioimaging and cancer therapy

X Zheng, Z Huang, Q Zhang, G Li, M Song, R Peng - Nanoscale, 2025 - pubs.rsc.org
Nucleic acids have enabled the fabrication of self-assemblies and dynamic operations.
Among different functional nucleic acids, aptamers can specifically bind to a wide range of …

[HTML][HTML] Aptamers used for molecular imaging and theranostics-recent developments

L Bohrmann, T Burghardt, C Haynes, K Saatchi… - Theranostics, 2022 - ncbi.nlm.nih.gov
Aptamers are single stranded oligonucleotides that fold into three dimensional structures
and are able to recognize a variety of molecular targets. Due to the similarity to antibodies …

Aptamers: features, synthesis and applications

A P. U, G Raj, J John, M Mohan K, F John… - Chemistry & …, 2023 - Wiley Online Library
Aptamers have become a topic of interest among the researchers and scientists since they
not only possess all of the benefits of antibodies but also possess special qualities including …

Bispecific aptamer-decorated and light-triggered nanoparticles targeting tumor and stromal cells in breast cancer derived organoids: implications for precision …

S Camorani, A Caliendo, E Morrone, L Agnello… - Journal of Experimental …, 2024 - Springer
Background Based on the established role of cancer-stroma cross-talk in tumor growth,
progression and chemoresistance, targeting interactions between tumor cells and their …

PET image-guided kidney injury theranostics enabled by a bipyramidal DNA framework

P Li, Z Huang, X Duan, T Wang, S Yang, D Jiang… - Biomaterials …, 2024 - pubs.rsc.org
Understanding the pharmacokinetic profiles of nanomaterials in living organisms is essential
for their application in disease treatment. Bipyramidal DNA frameworks (BDFs) are a type of …

Biosensors based on bivalent and multivalent recognition by nucleic acid scaffolds

H Kim, H Choi, Y Heo, C Kim, M Kim, KT Kim - Applied Sciences, 2022 - mdpi.com
Several biological macromolecules adopt bivalent or multivalent interactions to perform
various cellular processes. In this regard, the development of molecular constructs …