Neuroinflammation as a risk factor for attention deficit hyperactivity disorder

GA Dunn, JT Nigg, EL Sullivan - Pharmacology Biochemistry and Behavior, 2019 - Elsevier
Abstract Attention Deficit Hyperactivity Disorder (ADHD) is a persistent, and impairing
pediatric-onset neurodevelopmental condition. Its high prevalence, and recurrent …

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a …

B Leonard, M Maes - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
This paper reviews that cell-mediated-immune (CMI) activation and inflammation contribute
to depressive symptoms, including anhedonia; anxiety-like behaviors; fatigue and somatic …

Environmental enrichment alters neurobehavioral development following maternal immune activation in mice offspring with epilepsy

M Zeraati, N Najdi, B Mosaferi, AA Salari - Behavioural brain research, 2021 - Elsevier
Epilepsy is a chronic brain disease affecting millions of people worldwide. Anxiety-related
disorders and cognitive deficits are common in patients with epilepsy. Previous studies have …

What do microglia really do in healthy adult brain?

M Augusto-Oliveira, GP Arrifano, A Lopes-Araújo… - Cells, 2019 - mdpi.com
Microglia originate from yolk sac-primitive macrophages and auto-proliferate into adulthood
without replacement by bone marrow-derived circulating cells. In inflammation, stroke …

Molecular mechanisms in the regulation of adult neurogenesis during stress

M Egeland, PA Zunszain, CM Pariante - Nature Reviews Neuroscience, 2015 - nature.com
Coping with stress is fundamental for mental health, but understanding of the molecular
neurobiology of stress is still in its infancy. Adult neurogenesis is well known to be regulated …

Glucocorticoid-related molecular signaling pathways regulating hippocampal neurogenesis

C Anacker, A Cattaneo, A Luoni, K Musaelyan… - …, 2013 - nature.com
Stress and glucocorticoid hormones regulate hippocampal neurogenesis, but the molecular
mechanisms underlying their effects are unknown. We, therefore, investigated the molecular …

[HTML][HTML] Targeting neuroinflammation by polyphenols: A promising therapeutic approach against inflammation-associated depression

MA Tayab, MN Islam, KAA Chowdhury… - Biomedicine & …, 2022 - Elsevier
Depression is the most prevalent and debilitating mental disorder that affects a substantial
number of people globally, hindering all aspects of their lives and leading to a high number …

Developmental neuroinflammation and schizophrenia

U Meyer - Progress in Neuro-Psychopharmacology and …, 2013 - Elsevier
There is increasing interest in and evidence for altered immune factors in the etiology and
pathophysiology of schizophrenia. Stimulated by various epidemiological findings reporting …

Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target

F Caraci, SF Spampinato, MG Morgese… - Pharmacological …, 2018 - Elsevier
In the last several years a large number of studies have demonstrated the neurobiological
and clinical continuum between depression and Alzheimer's disease (AD). Depression is a …

Evidence for a dysregulated immune system in the etiology of psychiatric disorders

SM Gibney, HA Drexhage - Journal of Neuroimmune Pharmacology, 2013 - Springer
There is extensive bi-directional communication between the brain and the immune system
in both health and disease. In recent years, the role of an altered immune system in the …