Autoimmune diseases: targets, biology, and drug discovery

S Li, Y Wu, J Chen, S Shen, J Duan… - Acta Pharmacologica …, 2024 - nature.com
Autoimmune diseases (AIDs) arise from a breakdown in immunological self-tolerance,
wherein the adaptive immune system mistakenly attacks healthy cells, tissues and organs …

[HTML][HTML] Gut Microbiome Dysbiosis in Patients with Pemphigus and Correlation with Pathogenic Autoantibodies

SZ Li, QY Wu, Y Fan, F Guo, XM Hu, YG Zuo - Biomolecules, 2024 - mdpi.com
Background: Pemphigus is a group of potentially life-threatening autoimmune bullous
diseases induced by pathogenic autoantibodies binding to the surface of epidermal cells …

Comparative transcriptome analysis identifies Desmoglein-3 as a potential oncogene in oral cancer cells

H Wan, MT Teh, G Mastroianni, US Ahmad - Cells, 2023 - mdpi.com
The role of desmoglein-3 (DSG3) in oncogenesis is unclear. This study aimed to uncover
molecular mechanisms through comparative transcriptome analysis in oral cancer cells …

The emergence of circulating activated autoreactive desmoglein 3-specific follicular regulatory T cells is associated with long-term efficacy of rituximab in patients with …

V Hébert, J Novarino, M Maho-Vaillant… - British Journal of …, 2024 - academic.oup.com
Background Pemphigus vulgaris (PV) is characterized by autoantibodies targeting
keratinocyte adhesion proteins desmoglein (Dsg) 1 and 3, and by the human leukocyte …

Disruption of post-thymic tolerance in skin-reactive TCR transgenic mice through the interaction of lymphopenia and intestinal microbiota

H Hayabuchi, Y Tokifuji, H Takahashi… - International …, 2024 - academic.oup.com
Autoimmune diseases often arise from conditions where the immune system is
compromised. While lymphopenia-induced proliferation (LIP) is crucial for immune system …

The emergence of circulating activated autoreactive Dsg3-specific Tfr cells is associated with long-term efficacy of RTX in PV patients

V Hébert, J Novarino, M Maho-Vaillant… - British Journal of …, 2024 - academic.oup.com
Background Pemphigus vulgaris (PV) is characterized by autoantibodies targeting
keratinocytes adhesion proteins desmoglein (Dsg) 1 and 3, and by the HLA-DRB1-0402 …

[HTML][HTML] Pemphigus Vulgaris Unmasked in a Patient With Behçet's Disease: A Complex Diagnostic Dilemma

G Rios, K Gonzalez-Ramos, A Figueroa-Diaz… - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Behçet's disease (BD) is a systemic vasculitis characterized by recurrent painful oral and
genital ulcers, uveitis, and skin lesions. Pemphigus vulgaris (PV), on the other hand, is an …

Comparative transcriptome analysis identifies Desmoglein-3 as a potential oncogene in oral cancer

H Wan, MT Teh, G Mastroianni, US Ahmad - 2023 - preprints.org
The role of desmoglein-3 (DSG3) in oncogenesis is unclear. This study aimed to uncover
molecular mechanisms through comparative transcriptome analysis in oral cancer cells …

Pacientų, Sergančių Pūsline, Sociodemografinių Rodiklių, Ligos Eigos ir Gydymo Ypatumų 2017-2023 M. Retrospektyvinis Tyrimas

M Katutytė - 2024 - search.proquest.com
LIETUVOS SVEIKATOS MOKSLŲ UNIVERSITETAS MEDICINOS AKADEMIJA MEDICINOS
FAKULTETAS ODOS IR VENRINIŲ LIGŲ KLINIKA Martyna Katuty Page 1 1 LIETUVOS …

[引用][C] Vom Tumor zur Epidermolyse: mehrfach metastasierter solitärer fibröser Tumor mit paraneoplastischem Pemphigus

Z Yang, J Wang, R Shi, Q Da, X Zhao… - JDDG: Journal der …, 2023 - Wiley Online Library
Sehr geehrte Herausgeber, Eine 25-jährige Frau wurde im Juni 2020 wegen einer seit
einem Monat bestehenden schweren Epidermolyse zu uns überwiesen (Abbildung 1a). Im …