Scrub Typhus: The Geographic Distribution of Phenotypic and Genotypic Variants of Orientia tsutsugamushi

DJ Kelly, PA Fuerst, WM Ching… - Clinical infectious …, 2009 - academic.oup.com
Orientia tsutsugamushi is the etiological agent of scrub typhus, an acute, mite-borne, febrile
illness that occurs in the Asia-Pacific region. Historically, strain characterization used …

[HTML][HTML] Orientia tsutsugamushi infection: overview and immune responses

SY Seong, MS Choi, IS Kim - Microbes and Infection, 2001 - Elsevier
Orientia tsutsugamushi, an obligate intracellular bacterium, was isolated for the first time in
1930. Infections by virulent strains are characterized by fever, rash, eschar, pneumonia …

Development of a quantitative real-time polymerase chain reaction assay specific for Orientia tsutsugamushi

J Jiang, TC Chan, JJ Temenak, GA Dasch… - American Journal of …, 2004 - apps.dtic.mil
Two specific and sensitive polymerase chain reaction PCR assays were developed to detect
and quantitate Orientia tsutsugamushi, the agent of scrub typhus, using a portion of the 47 …

Scrub typhus serologic testing with the indirect immunofluorescence method as a diagnostic gold standard: a lack of consensus leads to a lot of confusion

SD Blacksell, NJ Bryant, DH Paris… - Clinical infectious …, 2007 - academic.oup.com
A review was performed to determine the evidence base for scrub typhus indirect
immunofluorescence assay (IFA) methodologies and the criteria for positive results. This …

[图书][B] Molecular detection of human bacterial pathogens

D Liu - 2011 - books.google.com
As more original molecular protocols and subsequent modifications are described in the
literature, it has become difficult for those not directly involved in the development of these …

Central nervous system involvement in patients with scrub typhus

H Pai, S Sohn, Y Seong, S Kee… - Clinical infectious …, 1997 - academic.oup.com
Scrub typhus, which is caused by Orientia tsutsugamushi, is a systemic illness that causes
generalized vasculitis. The central nervous system (CNS) is the most crucial target in other …

[PDF][PDF] Current status of tsutsugamushi disease in Korea

WH Chang - Journal of Korean medical science, 1995 - synapse.koreamed.org
Tsutsugamushi disease is a Ficketsia tsutsuga-mushi-bearing mite-borne illness
characterized by fever, headache, rash, and an esChar at the site of inoculating chigger bite …

[PDF][PDF] Comparative evaluation of selected diagnostic assays for the detection of IgG and IgM antibody to Orientia tsutsugamushi in Thailand.

RE Coleman, V Sangkasuwan… - The American journal …, 2002 - researchgate.net
We compared the performance of 2 commercially available dipstick assays, 2 enzyme-linked
immunosorbent assays (ELISAs), and an indirect immunofluorescent antibody (IFA) assay …

The validity of diagnostic cut-offs for commercial and in-house scrub typhus IgM and IgG ELISAs: A review of the evidence

K Saraswati, M Phanichkrivalkosil… - PLoS neglected …, 2019 - journals.plos.org
Background Scrub typhus is a neglected tropical disease that causes acute febrile illness.
Diagnosis is made based upon serology, or detection of the causative agent–Orientia …

Phylogenetic analysis of Orientia tsutsugamushi strains based on the sequence homologies of 56-kDa type-specific antigen genes

T Enatsu, H Urakami, A Tamura - FEMS microbiology letters, 1999 - academic.oup.com
Close and distant relationship among 31 strains of Orientia tsutsugamushi (20, two, one and
eight strains were isolated in Japan, Korea, China and southeast Asia, respectively) were …