The development of the concept of ferroptosis

T Hirschhorn, BR Stockwell - Free Radical Biology and Medicine, 2019 - Elsevier
The term ferroptosis was coined in 2012 to describe an iron-dependent regulated form of
cell death caused by the accumulation of lipid-based reactive oxygen species; this type of …

[HTML][HTML] Interplay of gut microbiota and oxidative stress: Perspective on neurodegeneration and neuroprotection

S Shandilya, S Kumar, NK Jha, KK Kesari… - Journal of Advanced …, 2022 - Elsevier
Background Recent research on the implications of gut microbiota on brain functions has
helped to gather important information on the relationship between them. Pathogenesis of …

[HTML][HTML] Ferroptosis in life: To be or not to be

L Xu, Y Liu, X Chen, H Zhong, Y Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Ferroptosis is a novel type of programmed cell death, characterized by a dysregulated iron
metabolism and accumulation of lipid peroxides. It features the alteration of mitochondria …

[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach… - Redox biology, 2017 - Elsevier
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Reactive oxygen species: Physiological and physiopathological effects on synaptic plasticity: Supplementary issue: Brain plasticity and repair

TF Beckhauser, J Francis-Oliveira… - Journal of …, 2016 - journals.sagepub.com
In the mammalian central nervous system, reactive oxygen species (ROS) generation is
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …

Ferroptosis and cardiovascular disease: role of free radical-induced lipid peroxidation

X Chen, X Li, X Xu, L Li, N Liang, L Zhang… - Free radical …, 2021 - Taylor & Francis
Cardiovascular disease (CVD), including heart attack, stroke, heart failure, arrhythmia, and
other congenital heart diseases remain the leading cause of morbidity and mortality …

Detection technologies for reactive oxygen species: fluorescence and electrochemical methods and their applications

S Duanghathaipornsuk, EJ Farrell, AC Alba-Rubio… - Biosensors, 2021 - mdpi.com
Reactive oxygen species (ROS) have been found in plants, mammals, and natural
environmental processes. The presence of ROS in mammals has been linked to the …

Activation of proinflammatory responses in cells of the airway mucosa by particulate matter: oxidant-and non-oxidant-mediated triggering mechanisms

J Øvrevik, M Refsnes, M Låg, JA Holme, PE Schwarze - Biomolecules, 2015 - mdpi.com
Inflammation is considered to play a central role in a diverse range of disease outcomes
associated with exposure to various types of inhalable particulates. The initial mechanisms …

Reactive oxygen species and synaptic plasticity in the aging hippocampus

F Serrano, E Klann - Ageing research reviews, 2004 - Elsevier
Aging is associated with a general decline in physiological functions including cognitive
functions. Given that the hippocampus is known to be critical for certain forms of learning …

Recent advances in fluorescent probes for the detection of reactive oxygen species

N Soh - Analytical and bioanalytical chemistry, 2006 - Springer
Reactive oxygen species (ROS) have captured the interest of many researchers in the
chemical, biological, and medical fields since they are thought to be associated with various …