Retinal changes in Alzheimer's disease—integrated prospects of imaging, functional and molecular advances
Alzheimer's Disease (AD) is a devastating neurodegenerative disorder of the brain, clinically
characterised by cognitive deficits that gradually worsen over time. There is, at present, no …
characterised by cognitive deficits that gradually worsen over time. There is, at present, no …
[HTML][HTML] Amyloid-beta and tau protein beyond Alzheimer's disease
The aggregation of amyloid-beta peptide and tau protein dysregulation are implicated to
play key roles in Alzheimer's disease pathogenesis and are considered the main …
play key roles in Alzheimer's disease pathogenesis and are considered the main …
Key genes and biochemical networks in various brain regions affected in Alzheimer's disease
M Abyadeh, N Tofigh, S Hosseinian, M Hasan… - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is one of the most complicated progressive neurodegenerative
brain disorders, affecting millions of people around the world. Ageing remains one of the …
brain disorders, affecting millions of people around the world. Ageing remains one of the …
Role of retinal amyloid-β in neurodegenerative diseases: overlapping mechanisms and emerging clinical applications
Amyloid-β (Aβ) accumulations have been identified in the retina for neurodegeneration-
associated disorders like Alzheimer's disease (AD), glaucoma, and age-related macular …
associated disorders like Alzheimer's disease (AD), glaucoma, and age-related macular …
Retinal dysfunction in Alzheimer's disease and implications for biomarkers
C Liao, J Xu, Y Chen, NY Ip - Biomolecules, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that manifests as
cognitive deficits and memory decline, especially in old age. Several biomarkers have been …
cognitive deficits and memory decline, especially in old age. Several biomarkers have been …
A proteomic view of cellular and molecular effects of cannabis
Cannabis (Cannabis sativa), popularly known as marijuana, is the most commonly used
psychoactive substance and is considered illicit in most countries worldwide. However, a …
psychoactive substance and is considered illicit in most countries worldwide. However, a …
Linking diabetes to Alzheimer's disease: potential roles of glucose metabolism and alpha-glucosidase
Alzheimer's disease (AD) and type 2 diabetes mellitus (DM) are more prevalent with ageing
and cause a substantial global socio-economic burden. The biology of these two conditions …
and cause a substantial global socio-economic burden. The biology of these two conditions …
Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide
The amyloid aggregation of peptides and proteins is a hallmark of neurological disorders
and type 2 diabetes. Human islet amyloid polypeptide (IAPP), co-secreted with insulin by …
and type 2 diabetes. Human islet amyloid polypeptide (IAPP), co-secreted with insulin by …
[HTML][HTML] ROS production and mitochondrial dysfunction driven by PU. 1-regulated NOX4-p22phox activation in Aβ-induced retinal pigment epithelial cell injury
J Sun, J Chen, T Li, P Huang, J Li, M Shen, M Gao… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Amyloid β (Aβ) deposition, an essential pathological process in age-related
macular degeneration (AMD), causes retinal pigment epithelium (RPE) degeneration driven …
macular degeneration (AMD), causes retinal pigment epithelium (RPE) degeneration driven …
Quantitative proteomics of sperm tail in asthenozoospermic patients: exploring the molecular pathways affecting sperm motility
Asthenozoospermia, characterized by low sperm motility, is one of the most common causes
of male infertility. While many intrinsic and extrinsic factors are involved in the etiology of …
of male infertility. While many intrinsic and extrinsic factors are involved in the etiology of …