Preeclampsia is a medical condition affecting 5–10% of pregnancies. It has serious effects
on the health of the pregnant mother and developing fetus. While possible causes of …

Preeclampsia (PE) is a hypertensive disease that affects pregnant women after 20 weeks of
gestation. This disease is associated with an important risk of maternal and fetal mortality …

Logistic regression is the primary analysis tool for binary traits in genome‐wide association
studies (GWAS). Multinomial regression extends logistic regression to multiple categories …

Women live longer than men but experience greater disability and a longer period of illness
as they age. Despite clear sex differences in aging, the impact of pregnancy and its …

Background Single nucleotide polymorphism (SNP) variants are abundant, persistent and
widely distributed across the genome and are frequently linked to the development of …

Preeclampsia (PE) is a common vascular disease of pregnancy with genetic predisposition.
Dysregulation of the complement system has been implicated, but molecular mechanisms …

Preeclampsia is a hypertensive disorder of pregnancy, which complicates up to 15% of US
deliveries. It is an idiopathic disorder associated with several different phenotypes. We …

ABSTRACT Background Adverse pregnancy outcomes (APOs) affect a large proportion of
pregnancies and represent an important cause of morbidity and mortality worldwide. Yet, the …

Background Toll-like receptor 4 (TLR4) plays a pivotal role in the innate immune response
and is hyperactivated in preeclampsia (PE). Several researchers have published conflicting …

Preeclampsia (PE) presents a major obstetrical problem for mother and fetus which is
characterized by the onset of hypertension and proteinuria in formerly normotensive women …